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| Product Name: | CT-1 | | Synonyms: | CT-1;Antigen MZ2-E;MAGE-1 human;Melanoma-associated antigen 1;Cardiotrophin-1 from mouse;Cardiophin 1;Anti-SLC6A8 antibody produced in goat;CRTR | | CAS: | 2155822-92-5 | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![CT-1 Structure]() |
| storage temp. | -20°C | | form | liquid | | color | off-white to yellow | | biological source | mouse |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26 | | WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids |
| Uses | Cardiotrophin-1 is from interleukin (IL)-6 family of cytokines. It is mainly present in adipose tissues, osteoclasts and cardiomyocytes. Cardiotrophin-1 works through gp130 (glycoprotein) and the LIFR (LIF receptor). | | Biological Activity | In adipocytes, cardiotrophin-1 helps in activating signaling pathways associated with metabolism. It controls energy homeostasis, and glucose and lipid metabolism. High levels of cardiotrophin-1 are reported in obesity and metabolic syndrome. Absence of cardiotrophin-1 in mice causes mature-onset obesity, insulin resistance and hypercholesterolemia. In osteoclasts, it enhances osteoblast activity as well as mineralization. It also participates in cardiomyocyte survival, hypertrophy, cardiac fibroblast proliferation and collagen type I synthesis. Cardiotrophin-1 is associated with arterial fibrosis and stiffness. |
| | CT-1 Preparation Products And Raw materials |
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