|
|
| | m-PEG7-t-butyl ester Basic information |
| Product Name: | m-PEG7-t-butyl ester | | Synonyms: | m-PEG7-t-butyl ester;m-PEG6-Boc;4,7,10,13,16,19,22-Heptaoxatricosanoic acid, 1,1-dimethylethyl ester;m-PEG7-Boc;m-PEG6-TBA;m-PEG7-COOtBu | | CAS: | 874208-90-9 | | MF: | C20H40O9 | | MW: | 424.53 | | EINECS: | | | Product Categories: | | | Mol File: | 874208-90-9.mol |  |
| | m-PEG7-t-butyl ester Chemical Properties |
| Boiling point | 467.7±40.0 °C(Predicted) | | density | 1.043±0.06 g/cm3(Predicted) |
| | m-PEG7-t-butyl ester Usage And Synthesis |
| Description | m-PEG7-t-butyl ester is a PEG linker containing a t-butyl ester. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media. | | Uses | m-PEG7-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs; Alkyl/ether | | References | [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005 |
| | m-PEG7-t-butyl ester Preparation Products And Raw materials |
|