| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Company Name: |
Sigma-Aldrich |
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
4-METHYLUMBELLIFERONE SODIUM SALT manufacturers
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| | 4-METHYLUMBELLIFERONE SODIUM SALT Basic information |
| Product Name: | 4-METHYLUMBELLIFERONE SODIUM SALT | | Synonyms: | 4-METHYLUMBELLIFERONE SODIUM SALT;4-methylumbelliferonesodium;7-hydroxy-4-methyl-2h-1-benzopyran-2-onesodiumsalt;methyl4umbelliferonesodium;7-HYDROXY-4-METHYLCOUMARIN SODIUM SALT;4-methyl-7-sodiooxy-2H-1-benzopyran-2-one;SODIUM 4-METHYL-2-OXO-CHROMEN-7-OLATE;7-Hydroxy-4-methylcoumarin hydrate sodium salt | | CAS: | 5980-33-6 | | MF: | C10H8O3.Na | | MW: | 199.16 | | EINECS: | 227-790-1 | | Product Categories: | | | Mol File: | 5980-33-6.mol |  |
| | 4-METHYLUMBELLIFERONE SODIUM SALT Chemical Properties |
| Melting point | 90-92 °C(lit.) | | storage temp. | Hygroscopic, -20°C Freezer, Under inert atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | crystalline | | color | yellow | | Water Solubility | water: 50mg/mL | | Stability: | Hygroscopic | | InChI | 1S/C10H8O3.Na/c1-6-4-10(12)13-9-5-7(11)2-3-8(6)9;/h2-5,11H,1H3;/q;+1/p-1 | | InChIKey | JGMQHDNPUCPRQE-UHFFFAOYSA-M | | SMILES | [Na+].CC1=CC(=O)Oc2cc([O-])ccc12 |
| Hazard Codes | T+ | | Risk Statements | 26/27/28 | | Safety Statements | 24/25 | | WGK Germany | 3 | | RTECS | GN7570000 | | Storage Class | 11 - Combustible Solids | | Toxicity | LD50 intraperitoneal in mouse: 325mg/kg |
| | 4-METHYLUMBELLIFERONE SODIUM SALT Usage And Synthesis |
| Uses | 4-Methylumbelliferone Sodium Salt forms a complex with metals such as copper (II), zinc (II), nickel (II), cobalt (II) and iron (III) which displays spasmolytic activity. Also, it inhibits the hyaluronan acid in cultured human skin fibroblasts. | | Biological Activity | 4-methylumbelliferone (4-MU) serves as a hyaluronan (HA) synthesis blocker. It exhibits anti-inflammatory, anti-fibrogenic, and antitumor properties. 4-MU is used to tre at biliary spasms and might also be beneficial in nonalcoholic steatohepatitis (NASH), inflammation, hepatocyte injury, and fibrotic response. 4-MU is known to be glucuronidated by most of the uridine 5ฺ-diphospho-glucuronosyltransferase (UGT) isoforms of the human liver. This makes it a potent probe substrate to examine the overall hepatic UGTs activity. |
| | 4-METHYLUMBELLIFERONE SODIUM SALT Preparation Products And Raw materials |
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