SLx-4090 manufacturers
- KD-026
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- $74.00
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2026-07-15
- CAS:913541-47-6
- Purity: 99.74%
- Supply Ability: 10g
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| | SLx-4090 Basic information |
| Product Name: | SLx-4090 | | Synonyms: | SLx-4090;KD-026 913541-47-6;2(1H)-Isoquinolinecarboxylic acid, 3,4-dihydro-6-[[[6-methoxy-4'-(trifluoromethyl)[1,1'-biphenyl]-2-yl]carbonyl]amino]-, phenyl ester;KD-026;KD 026,microsomal triglyceride transfer protein,MTP inhibitor,inhibit,Inhibitor,enterocytic-specific,dyslipidemia;KD-026, 10 mM in DMSO;Phenyl 6-(6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-ylcarboxamido)-3,4-dihydroisoquinoline-2(1H)-carboxylate;phenyl 6-(6-methoxy-4'-(trifluoromethyl)-[1,1'-biphenyl]-2-carboxamido)-3,4-dihydroisoquinoline-2(1h)-carboxylate | | CAS: | 913541-47-6 | | MF: | C31H25F3N2O4 | | MW: | 546.54 | | EINECS: | | | Product Categories: | | | Mol File: | 913541-47-6.mol |  |
| | SLx-4090 Chemical Properties |
| storage temp. | 4°C, protect from light | | solubility | DMSO: Sparingly soluble: 1-10 mg/mL
Ethanol: Slightly soluble: 0.1-1 mg/mL | | form | Solid | | color | White to off-white |
| | SLx-4090 Usage And Synthesis |
| Uses | SLX-4090 is an orally active enterocytic-specific microsomal triglyceride transfer protein (MTP) inhibitor with an IC50 of 8.0 nM. SLX-4090 can be used for the research of dyslipidemia[1]. | | in vivo | SLX-4090 (orally, 30 mg/kg) reduces postprandial lipids by 50% with an ED50 value 7 mg/kg in rats[1]. | | References | [1] Enoch Kim, et al. A small-molecule inhibitor of enterocytic microsomal triglyceride transfer protein, SLx-4090: biochemical, pharmacodynamic, pharmacokinetic, and safety profile. J Pharmacol Exp Ther. 2011 Jun;337(3):775-85. DOI:10.1124/jpet.110.177527 |
| | SLx-4090 Preparation Products And Raw materials |
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