8-iso Prostaglandin F1β manufacturers
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| | 8-iso Prostaglandin F1β Basic information |
| Product Name: | 8-iso Prostaglandin F1β | | Synonyms: | DZUXGQBLFALXCR-PZAYLFDTSA-N;8-iso Prostaglandin F1β;Prost-13-en-1-oic acid, 9,11,15-trihydroxy-, (8β,9β,11α,13E,15S)-;9β,11α,15S-trihydroxy-(8β)-prost-13E-en-1-oicacid | | CAS: | 26771-95-9 | | MF: | C20H36O5 | | MW: | 356.49684 | | EINECS: | | | Product Categories: | | | Mol File: | 26771-95-9.mol |  |
| | 8-iso Prostaglandin F1β Chemical Properties |
| Boiling point | 526.5±50.0 °C(Predicted) | | density | 1.136±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: >50 mg/ml (from PGF1a); DMSO: >50 mg/ml (from PGF1a); Ethanol: >75 mg/ml (from PGF1a); PBS pH 7.2: >2 mg/ml (from PGF1a) | | form | A crystalline solid | | pka | 4.78±0.10(Predicted) |
| | 8-iso Prostaglandin F1β Usage And Synthesis |
| Description | 8-iso PGF1β is a potential autoxidation product of DGLA. There are no published reports on its isolation from any biological source or on its biological activity. | | Uses | 8-iso Prostaglandin F1β is an isoprostane, that exhibits vasoconstrictive effect in neonatal porcine pulmonary arteries, pulmonary veins, and mesenteric arteries. 8-iso Prostaglandin F1β targets TXA2 receptor and exhibits the blood vessel contractile efficacy under the influence of tyrosine kinase and Rho kinase[1]. | | References | [1] González-Luis G, et al., Age-related differences in vasoconstrictor responses to isoprostanes in piglet pulmonary and mesenteric vascular smooth muscle. Pediatr Res. 2005 Jun;57(6):845-52. DOI:10.1203/01.PDR.0000161411.01208.83 |
| | 8-iso Prostaglandin F1β Preparation Products And Raw materials |
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