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Product Name:8-iso Prostaglandin E1;Alprostadil EP Impurity F
CAS:21003-46-3
Purity:95% HPLC Package:10mg;25mg;50mg;100mg
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Shanghai Kewel Chemical Co., Ltd.
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021-64609169 18901607656 |
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| Products Intro: |
Product Name:8-iso Prostaglandin E1
CAS:21003-46-3
Purity:95+ HPLC; Package:10mg;25mg;50mg;100mg
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| Company Name: |
Alfa Chemistry
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1-516-6625404 |
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| Products Intro: |
Product Name:8-iso Prostaglandin E1
CAS:21003-46-3
Purity:98% Package:1g;10g;100g;1KG;5KG
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| | Prostaglandin E1 Impurity 4 Basic information |
| Product Name: | Prostaglandin E1 Impurity 4 | | Synonyms: | GMVPRGQOIOIIMI-JCPCGATGSA-N;9-oxo-11α,15S-dihydroxy-(8β)-prost-13E-en-1-oic acid;OVINONIC ACID;9-Oxo-11aloha,15S-dihydroxy-(8beta)-prost-13E-en-1-oic acid;7-[(1S,2R,3R)-3-hydroxy-2-[(E,3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl]heptanoic acid;(-)-8-epi-PGE1;(8β,13E,15S)-11α,15-Dihydroxy-9-oxoprost-13-en-1-oic acid;8-Epiprostaglandin E1 | | CAS: | 21003-46-3 | | MF: | C20H34O5 | | MW: | 354.48 | | EINECS: | | | Product Categories: | | | Mol File: | 21003-46-3.mol |  |
| | Prostaglandin E1 Impurity 4 Chemical Properties |
| Melting point | 77-79 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3)) | | Boiling point | 529.3±50.0 °C(Predicted) | | density | 1.131±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: >100 mg/ml (from PGE1); DMSO: >50 mg/ml (from PGE1); Ethanol: >50 mg/ml (from PGE1); PBS pH 7.2: >1.6 mg/ml (from PGE1) | | form | A light yellow crystalline solid | | pka | 4.77±0.10(Predicted) |
| | Prostaglandin E1 Impurity 4 Usage And Synthesis |
| Description | Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E1 (8-iso PGE1) is an isoprostane which is found in human semen at levels of 7 μg/ml. It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF2α. | | Uses | Isoprostanes are a family of prostanoid molecules of non-cyclooxygenase origin. 8-iso Prostaglandin E1 (8-iso PGE1) is an isoprostane which is found in human semen at levels of 7 μg/ml. It is a pulmonary vasoconstrictor in anesthetized dogs with a potency similar to PGF2α.[Cayman Chemical] | | Uses | 8-Isoprostaglandin E1 has vasodilatory and electrophysiological actions porcine coronary artery. It also inhibits acetylcholine release from parasympathetic nerves innervating guinea-pig trachea mediation by prostanoid EP3 receptors. | | Definition | ChEBI: 8-Isoprostaglandin E1 is a prostanoid. | | References | [1] J D MORROW. A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.[J]. Proceedings of the National Academy of Sciences of the United States of America, 1990, 87 23: 9383-9387. DOI: 10.1073/pnas.87.23.9383
[2] TAYLOR P L. The 8-isoprostaglandins: Evidence for eight compounds in human semen[J]. Prostaglandins, 1979, 17 2: Pages 259-267. DOI: 10.1016/0090-6980(79)90046-7
[3] J NAKANO J M K. Effects of 8-isoprostaglandin E1 on the systemic and pulmonary circulations in dogs.[J]. Proceedings of the Society for Experimental Biology and Medicine, 1970, 133 4: 1314-1317. DOI: 10.3181/00379727-133-34679
[4] CATHERINE A. OPERE. Dual Effect of Isoprostanes on the Release of [3H]D-Aspartate from Isolated Bovine Retinae: Role of Arachidonic Acid Metabolites[J]. Neurochemical Research, 2005, 30 1: 129-137. DOI: 10.1007/s11064-004-9694-3 |
| | Prostaglandin E1 Impurity 4 Preparation Products And Raw materials |
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