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| | Arbaclofen Placarbil Basic information |
| Product Name: | Arbaclofen Placarbil | | Synonyms: | MUICUPWICXUNRS-GDCCIXDYSA-N;2-Thiophenecarboxylic acid, 5-(3,3-dimethyl-1-butyn-1-yl)-3-[[cis-4-hydroxy-4-[[[(3S)-tetrahydro-3-furanyl]oxy]methyl]cyclohexyl][[(1R)-4-methyl-3-cyclohexen-1-yl]carbonyl]amino]- | | CAS: | 1314795-11-3 | | MF: | C30H41NO6S | | MW: | 543.71 | | EINECS: | | | Product Categories: | | | Mol File: | 1314795-11-3.mol |  |
| | Arbaclofen Placarbil Chemical Properties |
| Boiling point | 721.2±60.0 °C(Predicted) | | density | 1.25±0.1 g/cm3(Predicted) | | pka | 3.67±0.10(Predicted) |
| | Arbaclofen Placarbil Usage And Synthesis |
| Uses | Radalbuvir (GS-9669) is a non-nucleoside inhibitor of nonstructural protein 5B (NS5B) RNA-dependent RNA polymerase (RdRp). Radalbuvir shows strong anti-HCV potency (GT1a intrinsic EC50 = 2.9 nM, GT1b EC50 = 6 nM)[1]. | | References | [1] Zhou Z, et al. Small molecule NS5B RdRp non-nucleoside inhibitors for the treatment of HCV infection: A medicinal chemistry perspective. Eur J Med Chem. 2022 Jul 8;240:114595. DOI:10.1016/j.ejmech.2022.114595 |
| | Arbaclofen Placarbil Preparation Products And Raw materials |
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