1,2-PHENYLENE PHOSPHOROCHLORIDATE manufacturers
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| | 1,2-PHENYLENE PHOSPHOROCHLORIDATE Basic information |
| Product Name: | 1,2-PHENYLENE PHOSPHOROCHLORIDATE | | Synonyms: | 3,2-benzodioxaphosphole,2-chloro-2-oxide;o-Phenylenephosphorochloridate;2-CHLORO-1,3,2-BENZODIOXAPHOSPHOLE 2-OXIDE;1,2-PHENYLENE PHOSPHOROCHLORIDATE, TECH.;1,2-PHENYLENE PHOSPHOROCHLORIDATE;1,2-PHENYLENE CHLOROPHOSPHATE;2-Chloro-1,3,2-benzodioxaphosphole 2-oxide, o-Phenylene chlorophosphate;o-Phenylene chlorophosphate | | CAS: | 1499-17-8 | | MF: | C6H4ClO3P | | MW: | 190.52 | | EINECS: | 216-106-7 | | Product Categories: | | | Mol File: | 1499-17-8.mol |  |
| | 1,2-PHENYLENE PHOSPHOROCHLORIDATE Chemical Properties |
| Melting point | 56-62 °C | | Boiling point | 120 °C9 mm Hg(lit.) | | density | 1.57±0.1 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Store in freezer, under -20°C | | form | solid | | BRN | 142368 | | InChI | 1S/C6H4ClO3P/c7-11(8)9-5-3-1-2-4-6(5)10-11/h1-4H | | InChIKey | KMWSGKPLIWNTEF-UHFFFAOYSA-N | | SMILES | ClP1(=O)Oc2ccccc2O1 | | EPA Substance Registry System | 1,3,2-Benzodioxaphosphole, 2-chloro-, 2-oxide (1499-17-8) |
| Hazard Codes | C | | Risk Statements | 14-34 | | Safety Statements | 26-36/37/39-45 | | RIDADR | UN 3261 8/PG 2 | | WGK Germany | 3 | | F | 10 | | TSCA | TSCA listed | | HazardClass | 8 | | PackingGroup | III | | Storage Class | 8A - Combustible corrosive hazardous materials | | Hazard Classifications | Skin Corr. 1B |
| | 1,2-PHENYLENE PHOSPHOROCHLORIDATE Usage And Synthesis |
| Uses | Reactant for preparation of:
- Uridine diphosphate-glucose derivatives as potential chain terminators of β-glucan biosynthesis with antifungal activity
- Vinyloxy phosphorus monomers
| | Preparation | 1,2-Phenylene phosphorochloridate is prepared by heating 2,2,2-trichloro-1,3,2-benzodioxaphosphole with a slight excess of acetic anhydride. | | reaction suitability | reaction type: Buchwald-Hartwig Cross Coupling Reaction
reaction type: Heck Reaction
reaction type: Hiyama Coupling
reaction type: Negishi Coupling
reaction type: Sonogashira Coupling
reaction type: Stille Coupling
reaction type: Suzuki-Miyaura Coupling | | Purification Methods | After distilling it in a vacuum, it sets to a colourless solid. It is soluble in pet ether, *benzene and slightly soluble in Et2O. [Khwaja et al. J Chem Soc (C) 2092 1970, Anschütz & Broeker Justus Liebigs Ann Chem 454 109 1927, Beilstein 6 IV 5602.] |
| | 1,2-PHENYLENE PHOSPHOROCHLORIDATE Preparation Products And Raw materials |
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