- EX229
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- $31.00
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2026-07-27
- CAS:1219739-36-2
- Purity: 99.20%
- Supply Ability: 10g
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| | ex229 (compound 991) Basic information |
| Product Name: | ex229 (compound 991) | | Synonyms: | ex229 (compound 991);EX-229;5-{[6-chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzimidazol-2-yl]oxy}-2-methylbenzoic acid;EX 229;EX229;Benzoic acid, 5-[[6-chloro-5-(1-methyl-1H-indol-5-yl)-1H-benzimidazol-2-yl]oxy]-2-methyl-;5-[[6-Chloranyl-5-(1-Methylindol-5-Yl)-1h-Benzimidazol-2-Yl]oxy]-2-Methyl-Benzoic Acid;AMPK Activator 991 (Compound 991);AMP-activated protein kinase,inhibit,EX 229,AMPK,Inhibitor,EX-229,EX229 | | CAS: | 1219739-36-2 | | MF: | C24H18ClN3O3 | | MW: | 431.87 | | EINECS: | | | Product Categories: | API | | Mol File: | 1219739-36-2.mol |  |
| | ex229 (compound 991) Chemical Properties |
| Boiling point | 706.4±70.0 °C(Predicted) | | density | 1.41±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:2): 0.30 mg/ml | | form | A solid | | pka | 3.40±0.25(Predicted) | | color | Off-white to pink |
| | ex229 (compound 991) Usage And Synthesis |
| Uses | AMPK Activator 991 is a small benzimidazole derivative that potently activates AMP-activated protein kinase (AMPK) to increase glucose transport in skeletal muscle, with possible applications in treating a variety of metabolic disorders, such as Type 2 diabetes. | | IC 50 | AMPK α1β1γ1: 0.06 μM (Kd); AMPK α2β1γ1: 0.06 μM (Kd); AMPK α1β2γ1: 0.51 μM (Kd) |
| | ex229 (compound 991) Preparation Products And Raw materials |
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