| Company Name: |
Ascent Scientific |
| Tel: |
4401179829988 |
| Email: |
customerservice@ascentscientific.co.uk |
| Company Name: |
Sigma-Aldrich |
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
(S)-3,5-DIHYDROXYPHENYLGLYCINE manufacturers
- (S)-3,5-DHPG
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- $456.00
-
2025-12-22
- CAS:162870-29-3
- Purity:
- Supply Ability: 10g
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| | (S)-3,5-DIHYDROXYPHENYLGLYCINE Basic information |
| Product Name: | (S)-3,5-DIHYDROXYPHENYLGLYCINE | | Synonyms: | (S)-3,5-DIHYDROXYPHENYLGLYCINE;(S)-3,5-DHPG;S-DHPG;(S)-3,5-Dihydroxyphenylglycine hydrate;+-2,5-DIMETHOXY-4-IODOAMPHETAMINE HYDROCHLORIDE;(S)-3,5-Dihydroxylphenylglycine;Benzeneacetic acid, α-amino-3,5-dihydroxy-, (αS)-;(2S)-2-amino-2-(3,5-dihydroxyphenyl)acetic acid | | CAS: | 162870-29-3 | | MF: | C8H9NO4 | | MW: | 183.16 | | EINECS: | 2017-001-1 | | Product Categories: | Glutamate receptor;Glutamate | | Mol File: | 162870-29-3.mol |  |
| | (S)-3,5-DIHYDROXYPHENYLGLYCINE Chemical Properties |
| Melting point | >207°C (dec.) | | Boiling point | 448.8±33.0 °C(Predicted) | | density | 1.550±0.06 g/cm3(Predicted) | | storage temp. | −20°C | | solubility | Aqueous Base (Very Slightly, Sonicated), Methanol (Slightly), Water (Slightly, Heated) | | pka | 1.77±0.10(Predicted) | | form | solid | | color | white | | Water Solubility | Soluble to 50 mM in water | | Stability: | Hygroscopic | | InChI | 1S/C8H9NO4.H2O/c9-7(8(12)13)4-1-5(10)3-6(11)2-4;/h1-3,7,10-11H,9H2,(H,12,13);1H2/t7-;/m0./s1 | | InChIKey | QZEFIWWBQUKNFA-FJXQXJEOSA-N | | SMILES | O.N[C@H](C(O)=O)c1cc(O)cc(O)c1 |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | (S)-3,5-DIHYDROXYPHENYLGLYCINE Usage And Synthesis |
| Uses | (S)-3,5-Dihydroxylphenylglycine is a potent agonist of group I metabotropic glutamate receptors mGluR1 and mGluR5. (S)-3,5-Dihydroxylphenylglycine have been utilized for the treatment of neuronal injury and cognitive enhancement. | | Uses | (S)-3,5-Dihydroxyphenylglycine hydrate has been used:
- as mGluR1/5agonist for metabotropic glutamate receptor 1 (mGluR1/5) activation in synaptoneurosomal preparations
- in ACSF for DHPG stimulation
- to inject into basolateral amygdala to study its effect on memory expression
| | Definition | ChEBI: (S)-3,5-dihydroxyphenylglycine is a glycine derivative that is L-alpha-phenylglycine substituted at positions 3 and 5 on the phenyl ring by hydroxy groups. It is a member of resorcinols and a non-proteinogenic L-alpha-amino acid. It is functionally related to a L-alpha-phenylglycine. It is a tautomer of a (S)-3,5-dihydroxyphenylglycine zwitterion. | | Biological Activity | Selective group I mGlu receptor agonist. Also available as part of the Group I mGlu Receptor Tocriset™ and Mixed mGlu Receptor Tocriset™ . | | Biochem/physiol Actions | (S)-3,5-Dihydroxyphenylglycine hydrate is a group I metabotropic glutamate receptor agonist. | | storage | -20°C (desiccate). Protect from light. |
| | (S)-3,5-DIHYDROXYPHENYLGLYCINE Preparation Products And Raw materials |
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