3-keto Sphinganine (d6:0) (hydrochloride)

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3-keto Sphinganine (d6:0) (hydrochloride) Basic information
Product Name:3-keto Sphinganine (d6:0) (hydrochloride)
Synonyms:3-keto Sphinganine (d6:0) (hydrochloride);2-amino-1-hydroxy-3-hexanone,monohydrochloride
CAS:1824544-52-6
MF:C6H14ClNO2
MW:167.63
EINECS:
Product Categories:
Mol File:1824544-52-6.mol
3-keto Sphinganine (d6:0) (hydrochloride) Structure
3-keto Sphinganine (d6:0) (hydrochloride) Chemical Properties
form A solid
Safety Information
MSDS Information
3-keto Sphinganine (d6:0) (hydrochloride) Usage And Synthesis
Description3-keto Sphinganine (d6:0) is a short-chain analog of the typical C18 chain-length 3-keto sphinganine (d18:0) . 3-keto Sphinganine (d18:0) is a lyso-sphingolipid formed by the condensation of L-serine and palmitoyl-CoA by serine palmitoyl transferase (SPT). Vitamin K deficiency inactivates SPT resulting in a decrease in the production of 3-keto sphinganine and other sphingolipids.1
Uses3-Keto sphinganine (d6:0) (3-Keto-C6-dihydrosphingosine) hydrochloride, an ester product, is a short-chain analog of 3-keto sphinganine. 3-keto sphinganine provokes the accumulation of dihydroshingolipids and induces autophagy in cancer cells[1].
References1. Batheja, A.D., Uhlinger, D.J., Carton, J.M., et al. Characterization of serine palmitoyltransferase in normal human tissues J. Histochem. Cytochem. 51(5),687-696(2003).
3-keto Sphinganine (d6:0) (hydrochloride) Preparation Products And Raw materials
Tag:3-keto Sphinganine (d6:0) (hydrochloride)(1824544-52-6) Related Product Information
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