RO-2468 manufacturers
- RO2468
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- $1520.00
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2026-04-21
- CAS:1360821-21-1
- Purity:
- Supply Ability: 10g
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| | RO-2468 Basic information |
| Product Name: | RO-2468 | | Synonyms: | RO-2468;Spiro[pyrrolidine-3,3'-[3H]pyrrolo[3,2-c]pyridine]-5-carboxamide, N-[4-(aminocarbonyl)-2-methoxyphenyl]-6'-chloro-4-(3-chloro-2-fluorophenyl)-2-(2,2-dimethylpropyl)-1',2'-dihydro-2'-oxo-, (2S,3R,4S,5R)- | | CAS: | 1360821-21-1 | | MF: | C30H30Cl2FN5O4 | | MW: | 614.49 | | EINECS: | | | Product Categories: | | | Mol File: | 1360821-21-1.mol |  |
| | RO-2468 Chemical Properties |
| Boiling point | 770.2±60.0 °C(Predicted) | | density | 1.44±0.1 g/cm3(Predicted) | | pka | 10.26±0.70(Predicted) |
| | RO-2468 Usage And Synthesis |
| Description | RO2468 is a potent and orally active p53-MDM2 inhibitor. | | Uses | RO 2468 is a potent, orally active and selective p53-MDM2 inhibitor. RO 2468 has anti-proliferative active. RO 2468 suppresses c growth in SJSA1 osteosarcoma models without obvious toxicity[1]. | | References | [1] Zhang Z, et, al. Discovery of Potent and Orally Active p53-MDM2 Inhibitors RO5353 and RO2468 for Potential Clinical Development. ACS Med Chem Lett. 2013 Dec 29;5(2):124-7. DOI:10.1021/ml400359z |
| | RO-2468 Preparation Products And Raw materials |
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