| Company Name: |
BOC Sciences |
| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
LDV FITC manufacturers
- LDV FITC
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- $1130.00
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2026-07-27
- CAS:1207610-07-8
- Purity:
- Supply Ability: 10g
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| | LDV FITC Basic information |
| Product Name: | LDV FITC | | Synonyms: | LDV FITC;LDV-Fluorescein Isothiocyanate | | CAS: | 1207610-07-8 | | MF: | C69H81N11O17S | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![LDV FITC Structure]() |
| | LDV FITC Chemical Properties |
| storage temp. | Store at -20°C | | solubility | Soluble to 1 mg/ml in PBS (pH 7.4) | | form | Powder | | color | Light yellow to yellow | | Sequence | {4-((N′-2-methylphenyl)ureido)-phenylacetyl}-Leu-Asp-Val-Pro-Ala-Ala-{Lys(FITC)} |
| | LDV FITC Usage And Synthesis |
| Description | Fluorescent ligand that binds to theα4β1integrin (VLA-4) with high affinity (Kdvalues are 0.3 nM and 12 nM for binding to U937 cells in the presence and absence of Mn2+respectively). Used to detect VLA-4 affinity and conformational changes. | | Uses | LDV-FITC, a fluorescent peptide, is a FITC-conjugated LDV peptide (HY-P2267). LDV-FITC binds to the α4β1 integrin with high affinity (Kd: 0.3 nM and 12 nM for binding to U937 cells in the presence and absence of Mn2+ respectively). LDV-FITC can be used to detect α4β1 integrin affinity[1][2]. | | storage | Store at -20°C | | References | [1] Hyduk SJ, et al. Phospholipase C, calcium, and calmodulin are critical for alpha4beta1 integrin affinity up-regulation and monocyte arrest triggered by chemoattractants. Blood. 2007 Jan 1;109(1):176-84. DOI:10.1182/blood-2006-01-029199
[2] Chigaev A, et al. Real time analysis of the affinity regulation of alpha 4-integrin. The physiologically activated receptor is intermediate in affinity between resting and Mn(2+) or antibody activation. J Biol Chem. 2001 Dec 28;276(52):48670-8. DOI:10.1074/jbc.M103194200 |
| | LDV FITC Preparation Products And Raw materials |
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