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Cyclo (Arg-Gly-Asp-D-Phe-Lys)

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Cyclo (Arg-Gly-Asp-D-Phe-Lys) Suppliers list
Company Name: Nanjing Peptide Biotech Ltd.  Gold
Tel: 025-58361106-805 15951641583
Email: zhao.xu@njpeptide.com
Company Name: Nanjing TGpeptide Biotechnology Co.,Ltd.  Gold
Tel: 18115476705
Email: sales@tgpeptide.com
Company Name: Nanjing Yuanpeptide Biotech Co.，Ltd.  Gold
Tel: 13357818155
Email: linhui@yuan-peptide.com
Company Name: Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd  Gold
Tel: 18020125070
Email: sales002@jszkhy.com
Company Name: ZHEJIANG HUAJUN PHARMACEUTICAL CO., LTD  Gold
Tel: 0571-17315361885 17315361885
Email: 15007824@QQ.COM

Cyclo (Arg-Gly-Asp-D-Phe-Lys) manufacturers

  • Cyclo(-RGDfK)
  • Cyclo(-RGDfK) pictures
  • $40.00
  • 2026-07-27
  • CAS:161552-03-0
  • Purity: 95.29%
  • Supply Ability: 10g
Cyclo (Arg-Gly-Asp-D-Phe-Lys) Basic information
Product Name:Cyclo (Arg-Gly-Asp-D-Phe-Lys)
Synonyms:cyclo (Arg-Gly-Asp-Phe-Lys);Cyclic RGDFK peptide;Cyclo(L-arginylglycyl-L-alpha-aspartyl-D-phenylalanyl-L-lysyl);Cyclo(-Arg-Gly-Asp-D-Phe-Lys) Trifluoroacetate salt;Cyclo (-RGDfK) TFA;Cyclo(RGDfK) peptide;CYCLO(RGDFK) PEPTIDE;CYCLIC RGDFK PEPTIDE;Cyclo(-RGDfK)(free base)
CAS:161552-03-0
MF:C27H41N9O7
MW:603.67
EINECS:
Product Categories:peptide;RGD
Mol File:Mol File
Cyclo (Arg-Gly-Asp-D-Phe-Lys) Structure
Cyclo (Arg-Gly-Asp-D-Phe-Lys) Chemical Properties
Melting point 191℃ (decomposition)
density 1.47±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility ≥30.19 mg/mL in DMSO; insoluble in EtOH; ≥59.2 mg/mL in H2O
form Powder
pka4.01±0.10(Predicted)
color White to off-white
SequenceCyclo(Arg-Gly-Asp-Phe-Lys)
InChIKeyNVHPXYIRNJFKTE-HAGHYFMRSA-N
SMILES[C@@H]1(NC(=O)[C@H](CC(=O)O)NC(=O)CNC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCCCN)NC1=O)CC1C=CC=CC=1
Safety Information
MSDS Information
Cyclo (Arg-Gly-Asp-D-Phe-Lys) Usage And Synthesis
UsesCyclo (-RGDfK) Trifluoroacetic Acid Salt is a potent inhibitor of αvβ3 integrin. Used in tumor therapy due to the targeting of the VEGFR2 gene by sRNA.
Biological Activityin one study where this peptide was labeled with 125i, it was found to bind specifically and with high affinity to αvβ3 receptors on neovascular blood vessel sections of different major human cancers. the integrin alpha(iib)beta(3)-specific cyclic hexapeptide contains an arg-gly-asp (rgd) sequence.
targetIntegrin
IC 50αvβ3: 0.94 nM (IC50)
Cyclo (Arg-Gly-Asp-D-Phe-Lys) Preparation Products And Raw materials
Raw materialsFmoc-Lys(Trt)-OH-->Fmoc-N'-Acetyl-L-lysine-->Fmoc-Asp(OtBu)-OH
Tag:Cyclo (Arg-Gly-Asp-D-Phe-Lys)(161552-03-0) Related Product Information
OPIORPHIN Bivalirudin trifluoroacetate salt H-Arg-Gly-Phe-Phe-OH 5-Benzyl-3,6-dioxo-2-piperazineacetic acid 3-carboxymethyl-6-benzyl-2,5-diketopiperazine H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-OH