| Company Name: |
Sigma-Aldrich
|
| Tel: |
021-61415566 800-8193336 |
| Email: |
orderCN@merckgroup.com |
| Products Intro: |
Product Name:Myeloperoxidase (MPO) Inhibitor Screening Kit (Fluorometric)
Purity:sufficient for 200?fluorometric?tests Package:1KT Remarks:MAK283-1KT
|
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Email: |
ordercn@merckgroup.com |
| Products Intro: |
Product Name:Myeloperoxidase (MPO) Inhibitor Screening Kit (Fluorometric)
|
|
| | MYELOPEROXIDASE (MPO) INHIBITOR SCREENING KIT (FLUOROMETRIC) Basic information |
| | MYELOPEROXIDASE (MPO) INHIBITOR SCREENING KIT (FLUOROMETRIC) Chemical Properties |
| Storage Class | 10 - Combustible liquids |
| | MYELOPEROXIDASE (MPO) INHIBITOR SCREENING KIT (FLUOROMETRIC) Usage And Synthesis |
| Uses | Suitable for screening/characterizing/studying potential inhibitors of Myeloperoxidase | | General Description | Myeloperoxidase (MPO: EC 1.11.2.2) is a peroxidase abundantly expressed in neutrophil granulocytes. It catalyzes the hydrogen peroxide dependent oxidation of halide ions to generate hypochlorite (HClO), the reaction by which MPO exhibits cytotoxic activity against tumor cells and microorganisms. MPO also oxidizes various substances such as phenol and anilines. MPO undergoes chlorination or peroxidation reaction depending upon the relative concentrations of chloride and the reducing substrates. Recent studies suggest that increased levels of MPO are associated with an increased risk for cardiovascular disease and myocardial infarction, thus development of novel and specific inhibitors of MPO is critical for therapeutic purposes. |
| | MYELOPEROXIDASE (MPO) INHIBITOR SCREENING KIT (FLUOROMETRIC) Preparation Products And Raw materials |
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