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Twochem Co.Ltd. |
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021-58111628 15800915896 |
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ST3932 manufacturers
- ST3932
-
- $1670.00
-
2026-04-21
- CAS:1246018-21-2
- Purity:
- Supply Ability: 10g
- ST3932
-
- $1670.00
-
2025-07-18
- CAS:1246018-21-2
- Purity:
- Supply Ability: 10g
|
| Product Name: | ST3932 | | Synonyms: | ST3932;ST-3932,ST3932;9H-Purine-2-propanol, 6-amino-α,9-dimethyl-8-(2H-1,2,3-triazol-2-yl)-;4-[6-Amino-9-methyl-8-(triazol-2-yl)purin-2-yl]butan-2-ol | | CAS: | 1246018-21-2 | | MF: | C12H16N8O | | MW: | 288.32 | | EINECS: | | | Product Categories: | | | Mol File: | 1246018-21-2.mol |  |
| | ST3932 Chemical Properties |
| Boiling point | 482.7±55.0 °C(Predicted) | | density | 1.62±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | Soluble in DMSO | | pka | 14.96±0.20(Predicted) |
| | ST3932 Usage And Synthesis |
| Description | ST3932 is a metabolite of ST1535, acts as an antagonist of adenosine A2A receptor, with Kis of 8 nM and 33 nM for A2A and A1 receptors, respectively. ST3932 is a metabolite of ST1535, acts as an antagonist of adenosine A2A receptor, with Kis of 8 nM and 33 nM for A2A and A1 receptors, respectively. ST3932 inhibits agonist-induced cAMP accumulation with an IC50 value of 450 nM[1]. ST3932 (10, 20, 40 mg/kg, p.o.) antagonizes haloperidol-induced catalepsy, and increases motor activity in mice. ST3932 (20, 40 mg/kg, i.p.) significantly increases the number of contralateral turns induced by l-DOPA in rats[1]. | | Uses | ST3932 is a metabolite of ST1535, acts as an antagonist of adenosine A2A receptor, with Kis of 8 nM and 33 nM for A2A and A1 receptors, respectively. | | in vivo | ST3932 (10, 20, 40 mg/kg, p.o.) antagonizes haloperidol-induced catalepsy, and increases motor activity in mice. ST3932 (20, 40 mg/kg, i.p.) significantly increases the number of contralateral turns induced by l-DOPA in rats[1]. | | References | [1]. ST3932, et al. Animal models of Parkinsons disease: Effects of two adenosine A2A receptor antagonists ST4206 and ST3932, metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535). Eur J Pharmacol. 2015 Aug 15;761:353-61. |
| | ST3932 Preparation Products And Raw materials |
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