YVAD-CHO (trifluoroacetate salt)

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YVAD-CHO (trifluoroacetate salt) Suppliers list
Company Name: Shanghai Hongye Biotechnology Co. Ltd  
Tel: 400-9205774 400-920-5774
Email: sales@glpbio.cn
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Tel: 18818260767
Email: sales@chemegen.com
YVAD-CHO (trifluoroacetate salt) Basic information
Product Name:YVAD-CHO (trifluoroacetate salt)
Synonyms:YVAD-CHO (trifluoroacetate salt)
CAS:
MF:
MW:0
EINECS:
Product Categories:
Mol File:Mol File
YVAD-CHO (trifluoroacetate salt) Structure
YVAD-CHO (trifluoroacetate salt) Chemical Properties
solubility Water: 1 mg/ml
Safety Information
MSDS Information
YVAD-CHO (trifluoroacetate salt) Usage And Synthesis
DescriptionYVAD-CHO is an inhibitor of caspase-1/interleukin-1β converting enzyme (ICE) and a non-acetylated form of Ac-YVAD-CHO (Item No. 10016).1 It prevents ICE-like and CPP32-like proteinase activity and inhibits apoptosis induced by ceramide or irinotecan (CPT-11; Item No. 14180) in 4B1 cells when used at a concentration of 600 µM. YVAD-CHO (100 µM) also prevents chromogranin A-induced cell death of primary rat microglia but not primary rat cerebellar granule neurons.2WARNING This product is not for human or veterinary use.
References[1] ATSUSHI SUZUKI . Sequential Operation of Ceramide Synthesis and ICE Cascade in CPT-11-Initiated Apoptotic Death Signaling[J]. Experimental cell research, 1997, 233 1: Pages 41-47. DOI: 10.1006/excr.1997.3498
[2] P. J. KINGHAM  J. M P  M L Cuzner. Apoptotic Pathways Mobilized in Microglia and Neurones as a Consequence of Chromogranin A-Induced Microglial Activation[J]. Journal of Neurochemistry, 2002, 73 2: 538-547. DOI: 10.1046/j.1471-4159.1999.0730538.x
YVAD-CHO (trifluoroacetate salt) Preparation Products And Raw materials
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