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| | 2,5-Di-tert-butyl-1,4-benzoquinone Basic information |
| Product Name: | 2,5-Di-tert-butyl-1,4-benzoquinone | | Synonyms: | 2,5-di-tert-butyl-p-benzoquinon;4-dione,2,5-bis(1,1-dimethylethyl)-5-cyclohexadiene-1;5-Cyclohexadiene-1,4-dione,2,5-bis(1,1-dimethylethyl)-2;2,5-DI-TERT-BUTYL-P-BENZOQUINONE;2,5-DI-TERT-BUTYL-1,4-BENZOQUINONE;2,5-DI-TERT-BUTYLBENZOQUINONE;2,5-Di-tert-butyl-2,5-cyclohexadiene-1,4-dione;25-DBQ | | CAS: | 2460-77-7 | | MF: | C14H20O2 | | MW: | 220.31 | | EINECS: | 219-552-0 | | Product Categories: | Anthraquinones, Hydroquinones and Quinones;Benzoquinones;C13 to C14;Carbonyl Compounds;Ketones | | Mol File: | 2460-77-7.mol |  |
| | 2,5-Di-tert-butyl-1,4-benzoquinone Chemical Properties |
| Melting point | 152-154 °C (lit.) | | Boiling point | 321.25°C (rough estimate) | | density | 1.0106 (rough estimate) | | vapor pressure | 0.241Pa at 20℃ | | refractive index | 1.4970 (estimate) | | storage temp. | Sealed in dry,Room Temperature | | form | powder to crystal | | color | White to Yellow to Orange | | Water Solubility | 18.716mg/L at 25℃ | | BRN | 2047945 | | InChI | 1S/C14H20O2/c1-13(2,3)9-7-12(16)10(8-11(9)15)14(4,5)6/h7-8H,1-6H3 | | InChIKey | ZZYASVWWDLJXIM-UHFFFAOYSA-N | | SMILES | CC(C)(C)C1=CC(=O)C(=CC1=O)C(C)(C)C | | LogP | 5.2 at 25℃ | | CAS DataBase Reference | 2460-77-7(CAS DataBase Reference) | | EPA Substance Registry System | 2,5-Cyclohexadiene-1,4-dione, 2,5-bis(1,1-dimethylethyl)- (2460-77-7) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | RTECS | GU5140000 | | TSCA | TSCA listed | | HS Code | 29146990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 | | Hazardous Substances Data | 2460-77-7(Hazardous Substances Data) |
| | 2,5-Di-tert-butyl-1,4-benzoquinone Usage And Synthesis |
| Chemical Properties | Yellow to golden crystalline powder | | Uses | 2,5-Di-tert-butyl-1,4-benzoquinone (DTBBQ) is an 2,5-disubstituted quinone. It is an antibacterial compound. It has been isolated from marine Streptomyces sp. VITVSK1. Pressure dependance on the intramolecular and intermolecular migration rates of Na+ and K+ in a 2,5-di-tert-butyl-1,4-benzoquinone ion pair have been evaluated by using a high-pressure EPR technique. | | Definition | ChEBI: 2,5-di-tert-Butyl-1,4-benzoquinone is a member of p-quinones and a member of benzoquinones. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 46, p. 4545, 1981 DOI: 10.1021/jo00335a045
Synthetic Communications, 10, p. 615, 1980 DOI: 10.1080/00397918008063598
Tetrahedron Letters, 35, p. 5083, 1994 DOI: 10.1016/S0040-4039(00)73327-2 | | General Description | 2,5-Di-tert-butyl-1,4-benzoquinone (DTBBQ) is an 2,5-disubstituted quinone. It is an antibacterial compound. It has been isolated from marine Streptomyces sp. VITVSK1. Pressure dependance on the intramolecular and intermolecular migration rates of Na+ and K+ in a 2,5-di-tert-butyl-1,4-benzoquinone ion pair have been evaluated by using a high-pressure EPR technique. | | Flammability and Explosibility | Flammable | | Synthesis | At 0 °C, 2,5-di-tert-butylhydroquinone (0.34 mmol) was dissolved in THF (1.0 mL) with Catalyst 2a (1.98 mg, 0.0034 mmol), and 30% aqueous H2O2 (50.0 mL, 0.44 mmol) was slowly added. The reaction mixture was stirred at 0 °C until the raw material was completely converted to 2,5-di-tert-butyl-1,4-benzoquinone. Upon completion of the reaction, the product was extracted with ether or dichloromethane, and the organic phase was dried over anhydrous Na2SO4 and concentrated under reduced pressure to afford the target compound 2,5-di-tert-butyl-1,4-benzoquinone. It is worth noting that the resulting product usually has high purity and can meet the requirements for subsequent use without further purification by column chromatography. | | References | [1] Bulletin of the Chemical Society of Japan, 1991, vol. 64, # 1, p. 336 - 338
[2] Organic and Biomolecular Chemistry, 2009, vol. 7, # 7, p. 1445 - 1453
[3] Synthesis, 2012, vol. 44, # 8, p. 1183 - 1189
[4] Tetrahedron, 1987, vol. 43, # 17, p. 3963 - 3974
[5] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981, p. 2970 - 2973 |
| | 2,5-Di-tert-butyl-1,4-benzoquinone Preparation Products And Raw materials |
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