(R*,S*)-(±)-2-Methyl-4aa-(3-hydroxyphenyl)-1,2,3,4,4a,5,12,12aa-octahydroquinolino[2,3,3-g]isoquinoline dihydrobromide

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(R*,S*)-(±)-2-Methyl-4aa-(3-hydroxyphenyl)-1,2,3,4,4a,5,12,12aa-octahydroquinolino[2,3,3-g]isoquinoline dihydrobromide Suppliers list
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(R*,S*)-(±)-2-Methyl-4aa-(3-hydroxyphenyl)-1,2,3,4,4a,5,12,12aa-octahydroquinolino[2,3,3-g]isoquinoline dihydrobromide manufacturers

  • TAN67
  • TAN67 pictures
  • $1260.00
  • 2026-07-15
  • CAS:1217628-73-3
  • Purity:
  • Supply Ability: 10g
(R*,S*)-(±)-2-Methyl-4aa-(3-hydroxyphenyl)-1,2,3,4,4a,5,12,12aa-octahydroquinolino[2,3,3-g]isoquinoline dihydrobromide Basic information
Product Name:(R*,S*)-(±)-2-Methyl-4aa-(3-hydroxyphenyl)-1,2,3,4,4a,5,12,12aa-octahydroquinolino[2,3,3-g]isoquinoline dihydrobromide
Synonyms:SB 205607 HCI
CAS:1217628-73-3
MF:C23H25BrN2O
MW:425.37
EINECS:
Product Categories:
Mol File:1217628-73-3.mol
(R*,S*)-(±)-2-Methyl-4aa-(3-hydroxyphenyl)-1,2,3,4,4a,5,12,12aa-octahydroquinolino[2,3,3-g]isoquinoline dihydrobromide Structure
(R*,S*)-(±)-2-Methyl-4aa-(3-hydroxyphenyl)-1,2,3,4,4a,5,12,12aa-octahydroquinolino[2,3,3-g]isoquinoline dihydrobromide Chemical Properties
solubility Soluble to 100 mM in water and to 100 mM in DMSO
form Powder
color White to off-white
Safety Information
MSDS Information
(R*,S*)-(±)-2-Methyl-4aa-(3-hydroxyphenyl)-1,2,3,4,4a,5,12,12aa-octahydroquinolino[2,3,3-g]isoquinoline dihydrobromide Usage And Synthesis
UsesSB 205607 Dihydrobromide is a selective δ-opioid receptor-1 agonist.
in vivo

TAN-67 (SB-205607; 1.5-4.5 mg/kg; i.v.; once) dihydrobromide reduces infarct volume in I/R-caused brain injury[2].
TAN-67 (3 mg/kg; i.v.; once) dihydrobromide improves survival and neurobehavioral performance after I/R[2].
TAN-67 (3 mg/kg; i.v.; once; adult C57BL/6J male mice) dihydrobromide increases both total APP and mature APP (APPm) levels and APP processing at an early time point (6 h)[2].

Animal Model:Adult C57BL/6J male mice with I/R-caused brain injury[2]
Dosage:1.5, 3.0, and 4.5 mg/kg
Administration:Intravenous injection; once
Result:Reduced infarct volume in a dose-dependent manner.
Animal Model:Adult C57BL/6J male mice with I/R-caused brain injury[2]
Dosage:3.0 mg/kg
Administration:Intravenous injection; once
Result:Had rapidly functional recovery than the vehicle-treated mice.
Reduced neuronal cell death.
Animal Model:Adult C57BL/6J male mice with transient middle cerebra artery occlusion (MCAO) ischemic stroke model[2]
Dosage:3.0 mg/kg
Administration:Intravenous injection; once
Result:Increased both total APP and mature APP (APPm) levels.
Reduced β-secretase activity.
IC 50δ Opioid Receptor/DOR: 0.647 nM (Ki)
storageStore at RT
(R*,S*)-(±)-2-Methyl-4aa-(3-hydroxyphenyl)-1,2,3,4,4a,5,12,12aa-octahydroquinolino[2,3,3-g]isoquinoline dihydrobromide Preparation Products And Raw materials
Tag:(R*,S*)-(±)-2-Methyl-4aa-(3-hydroxyphenyl)-1,2,3,4,4a,5,12,12aa-octahydroquinolino[2,3,3-g]isoquinoline dihydrobromide(1217628-73-3) Related Product Information
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