endo-BCN-PEG3-Biotin manufacturers
- endo-BCN-PEG3-Biotin
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2025-06-07
- CAS:1263166-92-2
- Min. Order: 10mg
- Purity: >95.00%
- Supply Ability: 50mg
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| | endo-BCN-PEG3-Biotin Basic information |
| Product Name: | endo-BCN-PEG3-Biotin | | Synonyms: | endo-BCN-PEG3-Biotin;BCN-endo-PEG3-Biotin;5,8,11-Trioxa-2,14-diazanonadecanoic acid, 19-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-15-oxo-, (1R,8S)-bicyclo[6.1.0]non-4-yn-9-ylmethyl ester;(1R,8S)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl 19-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-15-oxo-5,8,11-trioxa-2,14-diazanonadecanoate;(1α,8α,9β)-Bicyclo[6.1.0]non-4-yn-9-ylmethyl 19-[(3aS,4S,6aR)-hexahydro-2-oxo-1H | | CAS: | 1263166-92-2 | | MF: | C29H46N4O7S | | MW: | 594.76 | | EINECS: | | | Product Categories: | peg;ADC LINKER | | Mol File: | 1263166-92-2.mol |  |
| | endo-BCN-PEG3-Biotin Chemical Properties |
| Boiling point | 847.5±65.0 °C(Predicted) | | density | 1.25±0.1 g/cm3(Predicted) | | pka | 12.05±0.46(Predicted) | | form | Solid | | color | Off-white to light yellow |
| | endo-BCN-PEG3-Biotin Usage And Synthesis |
| Uses | BCN-PEG3-Biotin is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. BCN-PEG3-Biotin is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. | | IC 50 | Non-cleavable Linker | | References | [1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268 |
| | endo-BCN-PEG3-Biotin Preparation Products And Raw materials |
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