(4E)-TCO-PEG4-biotin manufacturers
- Biotin-PEG4-TCO
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2025-06-07
- CAS:2183440-30-2
- Min. Order: 1mg
- Purity: >95.00%
- Supply Ability: 1mg
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| | (4E)-TCO-PEG4-biotin Basic information |
| Product Name: | (4E)-TCO-PEG4-biotin | | Synonyms: | (4E)-TCO-PEG4-biotin;Biotin-PEG4-TCO;TCO-PEG4-biotin;5,8,11,14-Tetraoxa-2,17-diazadocosanoic acid, 22-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-18-oxo-, 4-cycloocten-1-yl ester;Novel Adjuvant TLR7 Agonist;EVs Stability PEG Modifier;Phycoerythrin Intermediate;Fluorescent Upconversion Nanoparticle Intermediate | | CAS: | 2183440-30-2 | | MF: | C29H50N4O8S | | MW: | 614.8 | | EINECS: | | | Product Categories: | peg | | Mol File: | 2183440-30-2.mol |  |
| | (4E)-TCO-PEG4-biotin Chemical Properties |
| Boiling point | 837.0±65.0 °C(Predicted) | | density | 1.21±0.1 g/cm3(Predicted) | | solubility | Soluble in DMSO, DCM, DMF | | pka | 11.95±0.46(Predicted) |
| | (4E)-TCO-PEG4-biotin Usage And Synthesis |
| Description | TCO-PEG4-biotin is a biotinylation reagent containing TCO moieties. TCO enable click chemistry with tetrazine. The hydrophilic PEG spacer improves the water solubility of compounds. | | Uses | TCO-PEG4-biotin is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1]. | | IC 50 | PEGs | | References | [1] Wang Y, et al. Degradation of proteins by PROTACs and other strategies. Acta Pharm Sin B. 2020 Feb;10(2):207-238. DOI:10.1016/j.apsb.2019.08.001 |
| | (4E)-TCO-PEG4-biotin Preparation Products And Raw materials |
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