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| | CLOCORTOLONE PIVALATE Basic information |
| Product Name: | CLOCORTOLONE PIVALATE | | Synonyms: | 9-chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3;CLOCORTOLONE PIVALATE (200 MG);9-chloro-6alpha-fluoro-11beta,21-dihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione 21-pivalate;clocortolone pivalate;9-Chloro-6α,11β-dihydroxy-21-pivaloyloxy-16α-methylpregna-1,4-diene-3,20-dione;SH-863;(6α,11β,16α)-9-Chloro-21-(2,2-diMethyl-1-oxopropoxy)-6-fluoro-11-hydroxy-16-Methypregna-1,4-diene-3,20-dione;9-Chloro-6α-fluoro-11β,21-dihydroxy-16α-Methylpregna-1,4-diene-3,20-dione 21-Pivalate | | CAS: | 34097-16-0 | | MF: | C27H36ClFO5 | | MW: | 495.02 | | EINECS: | 251-826-5 | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Steroids | | Mol File: | 34097-16-0.mol |  |
| | CLOCORTOLONE PIVALATE Chemical Properties |
| Melting point | 231-233°C | | Boiling point | 598.0±50.0 °C(Predicted) | | density | 1.24±0.1 g/cm3(Predicted) | | storage temp. | Refrigerator, under inert atmosphere | | solubility | Chloroform (Slightly), DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly) | | pka | 13.04±0.70(Predicted) | | form | Solid | | color | White |
| | CLOCORTOLONE PIVALATE Usage And Synthesis |
| Uses | Clocortolone Pivalate is a corticosteroid used in the treatment of atopic dermatitis. | | Definition | ChEBI: The 21-O-pivalate ester of clocortolone. It is used for the relief of inflammatory and pruritic (itching) skin disorders. | | Brand name | Cloderm (Healthpoint). | | General Description | Clocortolone pivalate, 9-chloro-21-(2,2-dimethyl-1-oxopropoxy)-6α-fluoro-11β-hydroxy-16α-methylpregna-1,4-diene-3,20-dione (Cloderm),along with desoximetasone, lacks the C17α oxygen functionalitythat is present in other GCs but still retains goodGC activity. |
| | CLOCORTOLONE PIVALATE Preparation Products And Raw materials |
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