TBOPP manufacturers
- TBOPP
-
- $89.00
-
2026-07-14
- CAS:1996629-79-8
- Purity: 99.79%
- Supply Ability: 10g
- TBOPP
-
- $89.00
-
2026-07-14
- CAS:1996629-79-8
- Purity: 99.79%
- Supply Ability: 10g
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| Product Name: | TBOPP | | Synonyms: | TBOPP;2(1H)-Pyridinone, 1-[2-oxo-2-[3'-(trifluoromethyl)[1,1'-biphenyl]-4-yl]ethyl]-5-(1-pyrrolidinylsulfonyl)-;1-(2-Oxo-2-(3'-(trifluoromethyl)-[1,1'-biphenyl]-4-yl)ethyl)-5-(pyrrolidin-1-ylsulfonyl)pyridin-2(1H)-one;Inhibitor,TBOPP,inhibit;1-[2-oxo-2-[4-[3-(trifluoromethyl)phenyl]phenyl]ethyl]-5-pyrrolidin-1-ylsulfonyl-pyridin-2-one;TBOPP, 10 mM in DMSO | | CAS: | 1996629-79-8 | | MF: | C24H21F3N2O4S | | MW: | 490.49 | | EINECS: | | | Product Categories: | API | | Mol File: | 1996629-79-8.mol |  |
| | TBOPP Chemical Properties |
| Boiling point | 645.4±65.0 °C(Predicted) | | density | 1.46±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: 125 mg/mL (254.85 mM) | | pka | -2.46±0.70(Predicted) | | form | Solid | | color | White to off-white |
| | TBOPP Usage And Synthesis |
| Uses | 1-(2-Oxo-2-(3''-(trifluoromethyl)-[1,1''-biphenyl]-4-yl)ethyl)-5-(pyrrolidin-1-ylsulfonyl)pyridin-2(1H)-one is a selective inhibitor of DOCK1 as a therapeutic approach to target cancer cell survival and invasion. | | in vivo | TBOPP (0.67 mg per mouse; administrated on days 0, 1, 3, and 5; for 2 weeks; C57BL/6 mice) treatment effectively suppresses metastasis of cancer cells in vivo and the number of lymphocytes in the spleen is not changed, the body weight is also unchanged between TBOPP-treated and non-treated mice[1]. | Animal Model: | C57BL/6 mice (6- to 8-week-old) with ex-3LL cells[1] | | Dosage: | 0.67 mg per mouse | | Administration: | Administrated on days 0, 1, 3, and 5; for 2 weeks | | Result: | The lung metastasis was significantly suppressed.
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| | TBOPP Preparation Products And Raw materials |
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