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| | (S)-1-(3-BROMOPHENYL)ETHANOL Basic information |
| Product Name: | (S)-1-(3-BROMOPHENYL)ETHANOL | | Synonyms: | (alphaS)-3-Bromo-alpha-methylbenzenemethanol;(S)-1-(3-BROMOPHENYL)ETHANOL;(S)-3-BROMO-ALPHA-METHYLBENZYL ALCOHOL;(S)-3-Bromo-alpha-methylbenzyl alcohol, 98% ee, 95%;(S)-3-Bromo-alpha-methylbenzyl alcohol, 95% (98% e.e.);(S)-3-Bromo-alpha-methylbenzyl alcohol, 95%, ee:98%;(1S)-1-(3-Bromophenyl)ethanol;(S)-3-Bromo-α-methylbenzyl alcohol | | CAS: | 134615-22-8 | | MF: | C8H9BrO | | MW: | 201.06 | | EINECS: | | | Product Categories: | | | Mol File: | 134615-22-8.mol |  |
| | (S)-1-(3-BROMOPHENYL)ETHANOL Chemical Properties |
| Boiling point | 264℃ | | density | 1.470 | | Fp | 114℃ | | storage temp. | 2-8°C | | form | Liquid | | pka | 14.35±0.20(Predicted) | | color | Clear colorless |
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ACROS
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| | (S)-1-(3-BROMOPHENYL)ETHANOL Usage And Synthesis |
| Chemical Properties | clear colorless liquid | | Synthesis | General procedure for the synthesis of 1-(3-bromophenyl)ethanol and (S)-1-(3-bromophenyl)ethanol from 3'-bromoacetophenone: under dry argon protection, the catalyst [0.4 mol% (complexes 12-22) or 0.2 mol% (dinuclear complex 24)] and 3'-bromoacetophenone (2.5 mmol) were added to a three necked Schlenk flask. The mixture was stirred at 82 °C for 15 min before adding 5 mL of a 0.06 M solution of base (Cs2CO3) in 2-propanol (0.3 mmol). The reaction progress was monitored by an HP-6890 gas chromatograph. In all reactions, only the corresponding alcohols and ketones were detected as products. Conversion rates and enantiomeric excess values (e.e. values) were determined by gas chromatography using a Supelco β-DEX 120 chiral capillary column. | | References | [1] Molecular Catalysis, 2018, vol. 456, p. 75 - 86
[2] Tetrahedron Letters, 2018, vol. 59, # 8, p. 719 - 722
[3] Angewandte Chemie, 1995, vol. 107, # 18, p. 2165 - 2166
[4] Angewandte Chemie, 1995, vol. 107, # 18, p. 2165 - 2166
[5] Journal of Organometallic Chemistry, 1997, vol. 547, # 1, p. 97 - 101 |
| | (S)-1-(3-BROMOPHENYL)ETHANOL Preparation Products And Raw materials |
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