NEUROPEPTIDE Y (HUMAN, RAT)

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NEUROPEPTIDE Y (HUMAN, RAT) Basic information
Product Name:NEUROPEPTIDE Y (HUMAN, RAT)
Synonyms:TYR-PRO-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-MET-ALA-ARG-TYR-TYR-SER-ALA-LEU-NH2: YPSKPDNPGEDAPAEDMARYYSAL-NH2;TYR-PRO-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-MET-ALA-ARG-TYR-TYR-SER-ALA-LEU-ARG-HIS-TYR-ILE-ASN-LEU-ILE-THR-ARG-GLN-ARG-TYR-NH2;Neuropeptide Y (free acid) (huMan, rat) NPY (free acid) (huMan, rat);[D-Trp34]-NPY, human-[D-Trp34];NPY FREE ACID (HUMAN, RAT);NPY (HUMAN, RAT);NEUROPEPTIDE Y FREE ACID (HUMAN, RAT);NEUROPEPTIDE Y, HUMAN
CAS:99575-89-0
MF:C189H285N55O57S
MW:0
EINECS:
Product Categories:Peptide
Mol File:Mol File
NEUROPEPTIDE Y (HUMAN, RAT) Structure
NEUROPEPTIDE Y (HUMAN, RAT) Chemical Properties
storage temp. -15°C
SequenceTyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr
Safety Information
MSDS Information
NEUROPEPTIDE Y (HUMAN, RAT) Usage And Synthesis
UsesNeuropeptide Y (human) free acid is the deamidated form of Neuropeptide Y (human, rat, mouse) (HY-P0198). The amidation of Neuropeptide Y C-terminal tyrosine is critical for its function. Non-amidated Neuropeptide Y fails to elicit G protein signaling[1][2][4].
References[1] Cajado et al. Neuropeptide Y family-degrading metallopeptidases in the Tityus serrulatus venom partially blocked by commercial antivenoms. Toxicol Sci. 2014 Dec;142(2):418-26. DOI:10.1093/toxsci/kfu193
[2] Sung CP, et al. Neuropeptide Y upregulates the adhesiveness of human endothelial cells for leukocytes. Circ Res. 1991 Jan;68(1):314-8. DOI:10.1161/01.res.68.1.314
[3] Gordon EA, et al. Characterization of functional neuropeptide Y receptors in a human neuroblastoma cell line. J Neurochem. 1990 Aug;55(2):506-13. DOI:10.1111/j.1471-4159.1990.tb04164.x
[4] Chaehee Park, et al. Structural basis of neuropeptide Y signaling through Y1 receptor. Nat Commun. 2022 Feb 14;13(1):853. DOI:10.1038/s41467-022-28510-6
NEUROPEPTIDE Y (HUMAN, RAT) Preparation Products And Raw materials
Tag:NEUROPEPTIDE Y (HUMAN, RAT)(99575-89-0) Related Product Information
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