NEUROPEPTIDE Y (HUMAN, RAT) manufacturers
|
| NEUROPEPTIDE Y (HUMAN, RAT) Basic information |
Product Name: | NEUROPEPTIDE Y (HUMAN, RAT) | Synonyms: | TYR-PRO-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-MET-ALA-ARG-TYR-TYR-SER-ALA-LEU-NH2: YPSKPDNPGEDAPAEDMARYYSAL-NH2;TYR-PRO-SER-LYS-PRO-ASP-ASN-PRO-GLY-GLU-ASP-ALA-PRO-ALA-GLU-ASP-MET-ALA-ARG-TYR-TYR-SER-ALA-LEU-ARG-HIS-TYR-ILE-ASN-LEU-ILE-THR-ARG-GLN-ARG-TYR-NH2;Neuropeptide Y (free acid) (huMan, rat)
NPY (free acid) (huMan, rat);[D-Trp34]-NPY, human-[D-Trp34];NPY FREE ACID (HUMAN, RAT);NPY (HUMAN, RAT);NEUROPEPTIDE Y FREE ACID (HUMAN, RAT);NEUROPEPTIDE Y, HUMAN | CAS: | 99575-89-0 | MF: | C189H285N55O57S | MW: | 0 | EINECS: | | Product Categories: | Peptide | Mol File: | Mol File | ![NEUROPEPTIDE Y (HUMAN, RAT) Structure]() |
| NEUROPEPTIDE Y (HUMAN, RAT) Chemical Properties |
storage temp. | -15°C | Sequence | Tyr-Pro-Ser-Lys-Pro-Asp-Asn-Pro-Gly-Glu-Asp-Ala-Pro-Ala-Glu-Asp-Met-Ala-Arg-Tyr-Tyr-Ser-Ala-Leu-Arg-His-Tyr-Ile-Asn-Leu-Ile-Thr-Arg-Gln-Arg-Tyr |
| NEUROPEPTIDE Y (HUMAN, RAT) Usage And Synthesis |
Uses | Neuropeptide Y (human) free acid is the deamidated form of Neuropeptide Y (human, rat, mouse) (HY-P0198). The amidation of Neuropeptide Y C-terminal tyrosine is critical for its function. Non-amidated Neuropeptide Y fails to elicit G protein signaling[1][2][4]. | References | [1] Cajado et al. Neuropeptide Y family-degrading metallopeptidases in the Tityus serrulatus venom partially blocked by commercial antivenoms. Toxicol Sci. 2014 Dec;142(2):418-26. DOI:10.1093/toxsci/kfu193 [2] Sung CP, et al. Neuropeptide Y upregulates the adhesiveness of human endothelial cells for leukocytes. Circ Res. 1991 Jan;68(1):314-8. DOI:10.1161/01.res.68.1.314 [3] Gordon EA, et al. Characterization of functional neuropeptide Y receptors in a human neuroblastoma cell line. J Neurochem. 1990 Aug;55(2):506-13. DOI:10.1111/j.1471-4159.1990.tb04164.x [4] Chaehee Park, et al. Structural basis of neuropeptide Y signaling through Y1 receptor. Nat Commun. 2022 Feb 14;13(1):853. DOI:10.1038/s41467-022-28510-6 |
| NEUROPEPTIDE Y (HUMAN, RAT) Preparation Products And Raw materials |
|