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| Product Name: | WRW4 | | Synonyms: | WRW4;TRP-ARG-TRP-TRP-TRP-TRP-NH2;WRW4,TFA;L-Tryptophanamide, L-tryptophyl-L-arginyl-L-tryptophyl-L-tryptophyl-L-tryptophyl-;WRWWWW-NH2;WRW4-NH2;(S)-N-((S)-1-(((S)-1-(((S)-1-(((S)-1-Amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)amino)-3-(1H-indol-3-yl)-1-oxopropan-2-yl)-2-((S)-2-amino-3-(1H-indol-3-yl)propanamido)-5-gua | | CAS: | 878557-55-2 | | MF: | C61H65N15O6 | | MW: | 1104.27 | | EINECS: | | | Product Categories: | N-Formyl Peptide receptor | | Mol File: | 878557-55-2.mol |  |
| density | 1.47±0.1 g/cm3(Predicted) | | storage temp. | Desiccate at -20°C | | pka | 13.37±0.46(Predicted) | | form | Solid | | color | White to off-white | | Water Solubility | Soluble to 1 mg/ml in Water | | Sequence | H-Trp-Arg-Trp-Trp-Trp-Trp-NH2 |
| Uses | WRW4, a specific formyl peptide receptor-like 1 (FPRL1) antagonist, inhibits WKYMVm binding to FPRL1 with an IC50 of 0.23 μM. WRW4 specifically inhibits the increase in intracellular calcium by the FPRL1 agonists MMK-1, amyloid beta42 (Abeta42) peptide, and F peptide[1]. | | storage | Store at -20°C | | References | [1] Bae YS, et al. Identification of peptides that antagonize formyl peptide receptor-like 1-mediated signaling. J Immunol. 2004;173(1):607-614. DOI:10.4049/jimmunol.173.1.607 |
| | WRW4 Preparation Products And Raw materials |
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