Gly-Gly-Gly-PEG4-methyltetrazine

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Company Name: Xi'an Confluore Biological Technology Co., Ltd.  
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Gly-Gly-Gly-PEG4-methyltetrazine manufacturers

Gly-Gly-Gly-PEG4-methyltetrazine Basic information
Product Name:Gly-Gly-Gly-PEG4-methyltetrazine
Synonyms:Gly-Gly-Gly-PEG4-methyltetrazine;Glycinamide, glycylglycyl-N-[2-[2-[2-[2-[4-(6-methyl-1,2,4,5-tetrazin-3-yl)phenoxy]ethoxy]ethoxy]ethoxy]ethyl]-
CAS:2353409-82-0
MF:C23H34N8O7
MW:534.57
EINECS:
Product Categories:ADC LINKER
Mol File:2353409-82-0.mol
Gly-Gly-Gly-PEG4-methyltetrazine Structure
Gly-Gly-Gly-PEG4-methyltetrazine Chemical Properties
density 1.263±0.06 g/cm3(Predicted)
solubility Soluble in Water, DMSO, DMF
pka13.57±0.46(Predicted)
Safety Information
MSDS Information
Gly-Gly-Gly-PEG4-methyltetrazine Usage And Synthesis
DescriptionGly-Gly-Gly-PEG4-methyltetrazine is a cleavable PEG linker used in the synthesis of antibody-drug conjugates.
UsesGly-Gly-Gly-PEG4-methyltetrazine is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
IC 50Cleavable Linker
References[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337. DOI:10.1038/nrd.2016.268
Gly-Gly-Gly-PEG4-methyltetrazine Preparation Products And Raw materials
Tag:Gly-Gly-Gly-PEG4-methyltetrazine(2353409-82-0) Related Product Information
2-[2-(2-Azidoethoxy)ethoxy]ethanamine 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid, 1-(2,5-dioxo-1-pyrrolidinyl) ester MC-Val-Cit-PAB DBCO-C6-NHS ester Maleimide-DOTA DBCO-NHS Ester