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Aikon International Limited
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Product Name:MORPHOLIN-4-YL-PHENYL-ACETIC ACID HYDROCHLORIDE
CAS:91641-50-8
Purity:95+% Package:1g;5g;10g
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| Company Name: |
Shanghai Jizhi Biochemical Technology Co. Ltd.
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021-4009004166/18616739031 18616739031 |
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| Products Intro: |
Product Name:2-Morpholino-2-phenylacetic acid hydrochloride
CAS:91641-50-8
Purity:95% Package:250mg;1g;5g Remarks:M70060
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| | MORPHOLIN-4-YL-PHENYL-ACETIC ACID HYDROCHLORIDE Basic information |
| Product Name: | MORPHOLIN-4-YL-PHENYL-ACETIC ACID HYDROCHLORIDE | | Synonyms: | MORPHOLIN-4-YL-PHENYL-ACETIC ACID HYDROCHLORIDE;2-morpholin-4-yl-2-phenylacetic acid,hydrochloride;2-Morpholino-2-phenylacetic acid hydrochloride;2-(Morpholin-4'-yl)phenylacetic acid hydrochloride;Morpholin-4-Yl-Phenyl-Acetic Acid Hydrochloride(WX665079) | | CAS: | 91641-50-8 | | MF: | C12H15NO3.ClH | | MW: | 257.71 | | EINECS: | | | Product Categories: | | | Mol File: | 91641-50-8.mol |  |
| | MORPHOLIN-4-YL-PHENYL-ACETIC ACID HYDROCHLORIDE Chemical Properties |
| storage temp. | Sealed in dry,Room Temperature |
| | MORPHOLIN-4-YL-PHENYL-ACETIC ACID HYDROCHLORIDE Usage And Synthesis |
| Synthesis | Preparation of 2-morpholino-2-phenylacetic acid hydrochloride (I39): ethyl 2-morpholino-2-phenylacetate (0.34 g, 1.36 mmol) was dissolved in dioxane (11.4 mL) and 37% hydrochloric acid (1.1 mL, 13.6 mmol) was added slowly and dropwise. The reaction mixture was stirred under reflux conditions overnight. 37% hydrochloric acid (1.1 mL, 13.6 mmol) was added again and the reaction was continued at reflux for 24 hours. Upon completion of the reaction, the solvent was removed by evaporation and the residue was ground with acetonitrile (10 mL) to afford 2-morpholino-2-phenylacetic acid hydrochloride as a white solid (0.22 g, 63.7% yield).1H NMR (300 MHz, DMSO-d6) δ 11.79 (s, 1H), 7.56-7.72 (m, 2H), 7.37-7.56 (m, 3H) , 5.25 (s, 1H), 3.60-4.10 (m, 4H), 3.27 (br.s, 2H), 2.96 (br.s, 2H). | | References | [1] Patent: WO2013/98145, 2013, A1. Location in patent: Page/Page column 50
[2] Patent: US2013/172302, 2013, A1. Location in patent: Paragraph 0177; 0180; 0181 |
| | MORPHOLIN-4-YL-PHENYL-ACETIC ACID HYDROCHLORIDE Preparation Products And Raw materials |
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