|
|
| | 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)- Basic information |
| Product Name: | 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)- | | Synonyms: | 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)-;2-(2,6-Dioxopiperidin-3-yl)-4-(prop-2-yn-1-ylamino)isoindoline-1,3-dione;2-(2,6-Dioxo-3-piperidyl)-4-(2-propynylamino)isoindoline-1,3-dione;Poma-C1-Alkyne;Thalidomide-4-NH-propargyl;Pomalidomide-propargyl;2-(2,6-Dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)-1H-isoindole-1,3(2H)-dione | | CAS: | 2154342-25-1 | | MF: | C16H13N3O4 | | MW: | 311.29 | | EINECS: | | | Product Categories: | | | Mol File: | 2154342-25-1.mol |  |
| | 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)- Chemical Properties |
| Boiling point | 610.9±55.0 °C(Predicted) | | density | 1.496±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C, protect from light, stored under nitrogen | | pka | 10.73±0.40(Predicted) | | form | Solid | | Appearance | Light yellow to yellow Solid |
| | 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)- Usage And Synthesis |
| Uses | Pomalidomide-propargyl contains an E3 ligand and a terminal alkyl group ready for click conjugation. Pomalidomide-propargyl is ready for conjugation to target proteins for PROTAC. |
| | 1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-(2-propyn-1-ylamino)- Preparation Products And Raw materials |
|