3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indole-5-carboxylic acid hydrochloride

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3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indole-5-carboxylic acid hydrochloride manufacturers
3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indole-5-carboxylic acid hydrochloride Basic information
Product Name:3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indole-5-carboxylic acid hydrochloride
Synonyms:CARMOXIROLE HYDROCHLORIDE;3-(4-(4-phenyl-5,6-dihydropyridin-1(2H)-yl)butyl)-1H-indole-5-carboxylic acid;3-<4-(1,2,3,6-Tetrahydro-4-phenyl-1-pyridyl)butyl>-5-indolcarbonsaeure;1H-Indole-5-carboxylic acid, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-;Carmoxirole (free base);3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indole-5-carboxylic acid hydrochloride
CAS:98323-83-2
MF:C24H27ClN2O2
MW:410.93638
EINECS:
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Mol File:98323-83-2.mol
3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indole-5-carboxylic acid hydrochloride Structure
3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indole-5-carboxylic acid hydrochloride Chemical Properties
Melting point 284-285°
Boiling point 621.5±55.0 °C(Predicted)
density 1.210±0.06 g/cm3(Predicted)
storage temp. Desiccate at +4°C
pka4.47±0.30(Predicted)
Safety Information
MSDS Information
3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indole-5-carboxylic acid hydrochloride Usage And Synthesis
UsesCarmoxirole is a selective, peripherally acting D2-like agonist.
DefinitionChEBI: An indolecarboxylic acid that is indole-5-carboxylic acid bearing an additional 4-(4-phenyl-1,2,3,6-tetrahydropyridin-1-yl)butyl substituent at position 3. Selective, peripherally acting dopamine D2 receptor agonist. Modulates noradren lin release and sympathetic activation. Displays antihypertensive properties in vivo.
Biological ActivitySelective, peripherally acting dopamine D 2 receptor agonist. Modulates noradrenalin release and sympathetic activation. Displays antihypertensive properties in vivo .
IC 50D2 Receptor
3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indole-5-carboxylic acid hydrochloride Preparation Products And Raw materials
Raw materials1H-Indole-5-carboxylic acid, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-, methyl ester
Tag:3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indole-5-carboxylic acid hydrochloride(98323-83-2) Related Product Information
3-[4-(3,6-Dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-1H-indole-5-carboxylic acid hydrochloride 3-[4-(4-Phenyl-1,2,3,6-tetrahydro-1-pyridyl)butyl]indole-5-carboxylic acid, 2HCl Indole-5-carboxylic acid 3-cyclohex-1-en-1-yl-1H-indole-6-carboxylic acid 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1H-indole 3-(1-Methyl-1,2,3,6-tetrahydro-4-pyridinyl)-1H-indole-6-carbonitrile