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| | KETOCONAZOLE INTERMEDIATE Basic information |
| Product Name: | KETOCONAZOLE INTERMEDIATE | | Synonyms: | KETOCONAZOLE INTERMEDIATE;cis-2-(2,4-dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol;[(R)-2-(2,4-DICHLORO-PHENYL)-2-IMIDAZOL-1-YLMETHYL-[1,3]DIOXOLAN-4-YL]-METHANOL;CIS-2-(2,4-DICHLOROPHENYL)-2- (1H-IMIDAZOL-1-YLMETHYL)-1,3;rel-2α*-(1H-Imidazole-1-ylmethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolane-4α*-methanol;(2R,4S)-rel-2-(2,4-dichlorophenyl)-2-(1H-iMidazol-1-ylMethyl)-1,3-dioxolane-4-Methanol;rac-Ketoconazole Hydroxymethyl Impurity;Ketoconazole Impurity 8 | | CAS: | 61397-58-8 | | MF: | C14H14Cl2N2O3 | | MW: | 329.18 | | EINECS: | 262-766-4 | | Product Categories: | Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 61397-58-8.mol |  |
| | KETOCONAZOLE INTERMEDIATE Chemical Properties |
| Melting point | 99-101 °C | | Boiling point | 529.1±50.0 °C(Predicted) | | density | 1.48±0.1 g/cm3(Predicted) | | storage temp. | Refrigerator | | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | | form | Solid | | pka | 14.20±0.10(Predicted) | | color | White |
| | KETOCONAZOLE INTERMEDIATE Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | cis-2-(2,4-Dichlorophenyl)-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolane-4-methanol is a Ketoconazole (K186000) fragment that may have modulatory activity on the large conductance calcium-activated potassium channel (BKCa). |
| | KETOCONAZOLE INTERMEDIATE Preparation Products And Raw materials |
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