一水没食子酸
| 中文名称 | 一水没食子酸 |
|---|---|
| 中文同义词 | 没食子酸 一水合物;没食子酸一水化合物;没食子酸,一水物(分析标准品,>99%(HPLC));没食子酸单水合物, ACS级;电子级没食子酸;没食子酸,一水物,AR,98.5%;没食子酸水合物;3,4,5-三羟基苯甲酸一水化物,99% |
| 英文名称 | Gallic acid monohydrate |
| 英文同义词 | Gallic Acid, Monohydrate, Crystal, Reagent, ACS;Gallic acid monohydrate >=99% (HPLC);Gallic acid monohydrate ACS reagent, >=98.0%;Gallic acid monohydrate Vetec(TM) reagent grade, 98%;Benzoic acid,3,4,5-trihydroxy-, hydrate (1:1);GALLIC ACID-1-HYDRATE;GALLIC ACID MONOHYDRATE;GALLIC ACID, HYDRATE |
| CAS号 | 5995-86-8 |
| 分子式 | C7H8O6 |
| 分子量 | 188.13 |
| EINECS号 | 611-919-7 |
| 相关类别 | 羰基化合物;有机化工;医药中间体;通用试剂;分析标准品;有机酸;食品和饮料标准品;羧酸;工业原料;化学试剂;医用原料;无机盐;植物提取物;生化试剂-其他化学试剂;化工;Pharmaceutical Intermediates;Antioxidant;Biochemistry;ACS Grade;Building Blocks;C7;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis;Essential Chemicals;Inorganic Salts;Organic Building Blocks;Research Essentials;一水没食子酸;无机盐;原料;添加剂;食品添加剂-食品原料;通用生化试剂-有机酸;原料药;Solutions and Reagents;Myrica cerifera;Acacia;Aspalathus linearis (Rooibos tea);Cimicifuga racemosa;Ephedra sinica;Euphorbia sp;Nutrition Research;Phytochemicals by Plant (Food/Spice/Herb);s wort);Vaccinium myrtillus (Bilberry) |
| Mol文件 | 5995-86-8.mol |
| 结构式 |  |
一水没食子酸 性质
| 熔点 | 252 °C (dec.)(lit.) |
|---|---|
| 密度 | 1.694 |
| 闪点 | 250 °C |
| 储存条件 | Keep in dark place,Sealed in dry,Room Temperature |
| 溶解度 | 溶于乙醇、乙醚、甘油、丙酮，微溶于苯、氯仿、石油醚。 |
| 形态 | 固体 |
| 颜色 | 白色至奶油色 |
| 水溶解性 | 15 g/l (20 ºC) |
| 敏感性 | Hygroscopic |
| Merck | 14,4345 |
| BRN | 2050274 |
| 稳定性 | 感光 |
| InChI | InChI=1S/C7H6O5.H2O/c8-4-1-3(7(11)12)2-5(9)6(4)10;/h1-2,8-10H,(H,11,12);1H2 |
| InChIKey | IUTKPPDDLYYMBE-UHFFFAOYSA-N |
| SMILES | C(O)(=O)C1=CC(O)=C(O)C(O)=C1.[H]O[H] |
| CAS 数据库 | 5995-86-8(CAS DataBase Reference) |
一水没食子酸是一种天然多羟基酚类化合物，具有抑制环氧合酶-2 (COX-2) 的自由基清除作用；在制药、食品、轻工诸方面均有广泛用途，也用作分析试剂，还用于制造墨水及照相业。
Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate 是一种天然多羟基酚类化合物，具有抑制环氧合酶-2 (COX-2) 的自由基清除作用。Gallic acid hydrate 具有多种活性，如抗菌、抗氧化、抗菌、抗炎和抗肿瘤活性。|
COX-2
|
Human Endogenous Metabolite
|
Gallic acid is an antioxidant which can inhibit both COX-2. After 18 h treatment with Gallic acid, the number of viable neutrophils is dramatically decreased from 40.3% to 27.7%, highly comparable with 26.4% for untreated neutrophils. Gallic acid fails to attenuate isoproterenol-induced myocytolysis.
The food intake (2.6±0.08 g/day, p=0.69) and the body weight (2.5±0.69 g, p=0.76) of the Gallic acid group do not differ significantly from those of the control group (food intake; 2.41±0.14 g/day and the body weight; 2.83±0.84 g/day). The blood glucose tolerance in the Gallic acid group is significantly improved after 2 weeks of treatment. The blood glucose tolerance of the Gallic acid group after a treatment period of 2 weeks is also significantly better than that of the control group at 90 and 120 min ( p<0.05). The serum triglyceride concentration in the Gallic acid group (0.67±0.03 mM, p<0.05) is significantly reduced relative to that of the control group (1.08±0.20 mM). The total cholesterol concentration is similar in the control (3.19±0.27 mM) and Gallic acid (3.01±0.18 mM) groups.
安全信息
| 危险品标志 | Xi |
|---|---|
| 危险类别码 | 36/37/38 |
| 安全说明 | 26-36-24/25 |
| WGK Germany | 2 |
| RTECS号 | LW7525000 |
| F | 8-9-23 |
| TSCA | Yes |
| 海关编码 | 29182900 |
| 提供商 | 语言 |
|---|---|
|
英文
|
|
|
英文
|
|
|
中文
|
|
|
英文
|