| Company Name: |
BOC Sciences
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| Tel: |
16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:Indoramine
CAS:26844-12-2
Purity:>95%
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| Company Name: |
Nanjing Shizhou Biology Technology Co.,Ltd
|
| Tel: |
025-025-85560043 17301488900 |
| Email: |
info@synzest.com |
| Products Intro: |
Product Name:N-{1-[2-(1H-indol-3-yl)ethyl]piperidin-4-yl}benzamide
CAS:26844-12-2
Purity:95% Package:1g；5g;10g
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| | Indoramin Basic information |
| Product Name: | Indoramin | | Synonyms: | Indoramine;N-[1-[2-(1H-Indol-3-yl)ethyl]piperidin-4-yl]benzamide;Wy-21901;Benzamide, N-[1-[2-(1H-indol-3-yl)ethyl]-4-piperidinyl]-;Indoramin USP/EP/BP | | CAS: | 26844-12-2 | | MF: | C22H25N3O | | MW: | 347.45 | | EINECS: | 248-041-5 | | Product Categories: | | | Mol File: | 26844-12-2.mol |  |
| | Indoramin Chemical Properties |
| Melting point | 208-210° | | Boiling point | 600.0±45.0 °C(Predicted) | | density | 1.21±0.1 g/cm3(Predicted) | | form | Solid | | pka | 14.32±0.20(Predicted) | | color | Off-white to light yellow |
| | Indoramin Usage And Synthesis |
| Originator | Baratol,Wyeth,UK,1981 | | Uses | Antihypertensive. | | Definition | ChEBI: Indoramin is a member of tryptamines. | | Manufacturing Process | 4-Benzamido-1-[2-(3-indolyl)ethyl] pyridinium bromide (3.0 g) was dissolved
in 91% ethanol (300 ml) containing triethylamine (0.08 g) and freshly
prepared W7 Raney nickel catalyst (ca 3 g) was added. The mixture was
hydrogenated in an autoclave at 400 psi hydrogen pressure and 50°C for 4
hours. After filtering off the catalyst the filtrate was evaporated in vacuo and
the residue was shaken with a mixture of chloroform and 2N sodium
hydroxide solution. The resulting insoluble material was filtered off and dried
to give 1.61 g of product, MP 203°C to 206°C. Recrystallization from ethanol
gave the title compound as colorless needles (1.34 g), MP 208°C to 210°C. | | Therapeutic Function | Antihypertensive |
| | Indoramin Preparation Products And Raw materials |
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