3-(allylsulphinyl)-L-alanine manufacturers
- (±)-Alliin
-
- $66.00 / 5mg
-
2026-01-05
- CAS:17795-26-5
- Min. Order:
- Purity: 99.86%
- Supply Ability: 10g
|
| | 3-(allylsulphinyl)-L-alanine Basic information |
| | 3-(allylsulphinyl)-L-alanine Chemical Properties |
| Boiling point | 416.1±45.0 °C(Predicted) | | density | 1.354±0.06 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | PBS (pH 7.2): 10 mg/ml | | form | A crystalline solid | | pka | 1.88±0.10(Predicted) | | color | White to light yellow | | BRN | 1724805 | | InChI | 1S/C6H11NO3S/c1-2-3-11(10)4-5(7)6(8)9/h2,5H,1,3-4,7H2,(H,8,9)/t5-,11?/m0/s1 | | InChIKey | XUHLIQGRKRUKPH-ITZCMCNPSA-N | | SMILES | N[C@@H](CS(=O)CC=C)C(O)=O |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26 | | WGK Germany | 3 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 3-(allylsulphinyl)-L-alanine Usage And Synthesis |
| Description | Alliin is a cysteine sulfoxide constituent of garlic that is converted by alliinase to allicin, which imparts its pungent aroma and flavor. Alliin exhibits anti-cancer, anti-microbial, anti-hypertensive, cardioprotective, and anti-oxidant activities. It has been shown to inhibit squalene monooxygenase, a rate-limiting step in the downstream pathway of cholesterol biosynthesis, with an IC50 value of 120 μM. | | Uses | rac-Alliin has shown notable preventive effects on cardiac marker enzymes and lipids in isoproterenol-induced myocardial injury. rac-Alliin is also known to exhibit anticancer, antimicrobial, antihypertensive, antioxidant activities. | | Uses | (±)-L-Alliin has been used in nutrient broth No. 2 (NB2) for determining the concentrations of garlic-derived products active against Clostridium jejuni. | | Definition | ChEBI: 3-(Allylsulphinyl)-L-alanine is a L-alpha-amino acid. | | General Description | Alliin is the precursor of allicin. | | Biochem/physiol Actions | S-Allyl-L-cysteine ((±)-L-Alliin) (SAC) may be used to study its potential as an anti-Alzheimer′s factor. SAC has been shown to increase cell proliferation and neuroblast differentiation by increasing 5-HT(1A) and provide antioxidative benefit to neurons and synapses. | | References | [1] TVRTKO KARLO KOVA?EVI?. The Interplay of Physiological and Biochemical Response to Short-Term Drought Exposure in Garlic (Allium sativum L.).[J]. Plants-Basel, 2023, 12 18. DOI: 10.3390/plants12183215
[2] CHIEKO OHSUMI Konosuke S Takahisa Hayashi. Formation of alliin in the culture tissues of Allium sativum. Oxidation of S-allyl-l-cysteine[J]. Phytochemistry, 1993, 33 1: Pages 107-111. DOI: 10.1016/0031-9422(93)85404-f
[3] S.M. ASDAQ M. N I. Potential of garlic and its active constituent, S-allyl cysteine, as antihypertensive and cardioprotective in presence of captopril[J]. Phytomedicine, 2010, 17 13: Pages 1016-1026. DOI: 10.1016/j.phymed.2010.07.012
[4] JI-MYUNG KIM. Structure?Activity Relationship of Neuroprotective and Reactive Oxygen Species Scavenging Activities for Allium Organosulfur Compounds[J]. Journal of Agricultural and Food Chemistry, 2006, 54 18: 6547-6553. DOI: 10.1021/jf060412c
[5] XAVIER LIEBEN LOUIS. Garlic extracts prevent oxidative stress, hypertrophy and apoptosis in cardiomyocytes: a role for nitric oxide and hydrogen sulfide.[J]. BMC Complementary and Alternative Medicine, 2012, 12: 140. DOI: 10.1186/1472-6882-12-140
[6] RADU VASILE BAGIU Monica B Brigitha Vlaicu. Chemical composition and in vitro antifungal activity screening of the Allium ursinum L. (Liliaceae).[J]. International Journal of Molecular Sciences, 2012, 13 2: 1426-1436. DOI: 10.3390/ijms13021426 |
| | 3-(allylsulphinyl)-L-alanine Preparation Products And Raw materials |
|