Octanoic acid, 2-butyl-, 1,1'-[[(3-hydroxypropyl)imino]di-9,1-nonanediyl] ester

Request For Quotation
Octanoic acid, 2-butyl-, 1,1'-[[(3-hydroxypropyl)imino]di-9,1-nonanediyl] ester Suppliers list
Company Name: SHAANXI DIDEU MEDICHEM CO.LTD  
Tel: 029-029-81123119 17391733320
Email: 1021@dideu.com
Company Name: Shanghai Yifei Biotechnology Co. , Ltd.  
Tel: 021-65675885 18964387627
Email: customer_service@efebio.com
Company Name: Jilin Chinese Academy of Sciences-yanshen Technology  
Tel: 18143011203
Email: ET-market@chemextension.com
Company Name: Shandong Dayou Pharmaceutical Research and Development Co., Ltd.  
Tel: hanfangpharma@126.com 15165037910
Email: hanfangpharma@126.com
Company Name: Pharmalego  
Tel: 18321033991
Email: marketing@pharmalego.com
Octanoic acid, 2-butyl-, 1,1'-[[(3-hydroxypropyl)imino]di-9,1-nonanediyl] ester Basic information
Product Name:Octanoic acid, 2-butyl-, 1,1'-[[(3-hydroxypropyl)imino]di-9,1-nonanediyl] ester
Synonyms:Octanoic acid, 2-butyl-, 1,1'-[[(3-hydroxypropyl)imino]di-9,1-nonanediyl] ester;Lipid III-45;9-[(9-[(2-butyloctanoyl)oxy]nonyl)(3-hydroxypropyl)amino]nonyl 2-butyloctanoate;2-butyl-Octanoic acid 1,1'-[[(3-hydroxypropyl)imino]di-9,1-nonanediyl] ester
CAS:2096984-25-5
MF:C45H89NO5
MW:724.19
EINECS:
Product Categories:
Mol File:2096984-25-5.mol
Octanoic acid, 2-butyl-, 1,1'-[[(3-hydroxypropyl)imino]di-9,1-nonanediyl] ester Structure
Octanoic acid, 2-butyl-, 1,1'-[[(3-hydroxypropyl)imino]di-9,1-nonanediyl] ester Chemical Properties
Boiling point 732.7±30.0 °C(Predicted)
density 0.923±0.06 g/cm3(Predicted)
solubility Ethanol: 10 mg/ml
pka14.99±0.10(Predicted)
Safety Information
MSDS Information
Octanoic acid, 2-butyl-, 1,1'-[[(3-hydroxypropyl)imino]di-9,1-nonanediyl] ester Usage And Synthesis
DescriptionLipid III-45 is an ionizable cationic lipid (pKa = 6.25).1 It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA in vivo.1,2,3 LNPs containing lipid III-45 and encapsulating a luciferase mRNA reporter accumulate in liver and adipose tissue in mice.1,2 LNPs containing lipid III-45 have been used to deliver an mRNA sequence encoding an antibody targeting the tumor-associated antigen and tight junction integral protein claudin-18 isoform 2 (claudin-18.2) to mice and reduce tumor volume in an MDA-MB-231 mouse xenograft model.3WARNING This product is not for human or veterinary use.
References[1] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
[2] ARCHER D F. Delivery of therapeutic agents to the target tissue.[J]. Menopause: The Journal of The North American Menopause Society, 2011, 18 10: 1040-1041. DOI: 10.1097/gme.0b013e31822ff238
[3] De Souza, F.I., Zumiotti, A.V., and Da Silva, C.F. Neuregulins 1-α and 1-β on the regeneration the peripheral nerves[J]. Acta Ortop Bras.
Octanoic acid, 2-butyl-, 1,1'-[[(3-hydroxypropyl)imino]di-9,1-nonanediyl] ester Preparation Products And Raw materials
Tag:Octanoic acid, 2-butyl-, 1,1'-[[(3-hydroxypropyl)imino]di-9,1-nonanediyl] ester(2096984-25-5) Related Product Information
2-Hexadecanol, 1,1′-[[3-[4-[2-[[3-[bis(2-hydroxyhexadecyl)amino]-2-ethoxypropyl](2-hydroxyhexadecyl)amino]ethyl]-1-piperazinyl]-2-ethoxypropyl]imino]bis- Lipid A4 Lipid HTO12 Lipid ND-O1