(S)-1-((S)-2-Hydroxy-2-(4-(5-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)piperidine-3-carboxylic acid
| 中文名称 | (S)-1-((S)-2-Hydroxy-2-(4-(5-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)piperidine-3-carboxylic acid |
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| 中文同义词 | 化合物 T26866;化合物BMS-960 |
| 英文名称 | (S)-1-((S)-2-Hydroxy-2-(4-(5-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)piperidine-3-carboxylic acid |
| 英文同义词 | (S)-1-((S)-2-Hydroxy-2-(4-(5-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)piperidine-3-carboxylic acid;BMS 960;BMS960;BMS-960;3-Piperidinecarboxylic acid, 1-[(2S)-2-hydroxy-2-[4-[5-[3-phenyl-4-(trifluoromethyl)-5-isoxazolyl]-1,2,4-oxadiazol-3-yl]phenyl]ethyl]-, (3S)- |
| CAS号 | 1265321-86-5 |
| 分子式 | C26H23F3N4O5 |
| 分子量 | 528.48 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 1265321-86-5.mol |
| 结构式 |  |
(S)-1-((S)-2-Hydroxy-2-(4-(5-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)piperidine-3-carboxylic acid 性质
| 沸点 | 745.3±70.0 °C(Predicted) |
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| 密度 | 1.387±0.06 g/cm3(Predicted) |
| 酸度系数(pKa) | 3.84±0.20(Predicted) |
(S)-1-((S)-2-Hydroxy-2-(4-(5-(3-phenyl-4-(trifluoromethyl)isoxazol-5-yl)-1,2,4-oxadiazol-3-yl)phenyl)ethyl)piperidine-3-carboxylic acid 用途与合成方法
BMS-960 free base 是一种强效且选择性的含有异噁唑的 S1P1 受体激动剂，可以用于免疫性疾病和血管疾病的研究。