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| | sodium 2-(3-benzoylphenyl)propionate Basic information |
| Product Name: | sodium 2-(3-benzoylphenyl)propionate | | Synonyms: | sodium 2-(3-benzoylphenyl)propionate;19583-RP sodium;19583-RP-Na;3-Benzoyl-α-methylbenzeneacetic acid sodium salt;Ketoprofen sodium;Sodium ketoprofen;KETOPROFEN SODIUM SALT;sodium,2-(3-benzoylphenyl)propanoate | | CAS: | 57495-14-4 | | MF: | C16H13NaO3 | | MW: | 276.26239 | | EINECS: | 260-770-0 | | Product Categories: | | | Mol File: | 57495-14-4.mol |  |
| | sodium 2-(3-benzoylphenyl)propionate Chemical Properties |
| | sodium 2-(3-benzoylphenyl)propionate Usage And Synthesis |
| Uses | Ketoprofen (RP-19583) sodium is a non-steroidal anti-inflammatory agent. Ketoprofen sodium can inhibit the activity of Cyclooxygenase with IC50 values of 2 nM (COX-1) and 26 nM (COX-2). Ketoprofen is potential in the research of inflammation, immunology, and metabolic disease such as obesity[1][2][3]. | | References | [1] Palomer A, et al. Structure-based design of cyclooxygenase-2 selectivity into ketoprofen. Bioorg Med Chem Lett. 2002 Feb 25;12(4):533-7. DOI:10.1016/s0960-894x(01)00800-9
[2] NamHyeon Kang Ketoprofen alleviates diet-induced obesity and promotes white fat browning in mice via the activation of COX-2 through mTORC1-p38 signaling pathway. Pflugers Arch. 2020 May;472(5):583-596. DOI:10.1097/j.pain.0000000000000171
[3] Denisa Dan, et al. Ketoprofen affects the mammary immune response in dairy cows in vivo and in vitro. J Dairy Sci. 2018 Dec;101(12):11321-11329. DOI:10.3168/jds.2018-15034 |
| | sodium 2-(3-benzoylphenyl)propionate Preparation Products And Raw materials |
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