BHV-4157 HCl salt

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Company Name:	Shanghai Beckham Medical Technology Co., Ltd
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BHV-4157 HCl salt Basic information

Product Name:	BHV-4157 HCl salt
Synonyms:	BHV-4157 HCl salt;Troriluzole-(HCl salt);2-(2-Aminoacetamido)-N-methyl-N-(2-oxo-2-((6-(trifluoromethoxy)benzo[d]thiazol-2-yl)amino)ethyl)acetamide hydrochloride;Troriluzole hydrochloride
CAS:	1926204-76-3
MF:	C15H17ClF3N5O4S
MW:	455.84
EINECS:
Product Categories:
Mol File:	1926204-76-3.mol

BHV-4157 HCl salt Chemical Properties

Safety Information

MSDS Information

BHV-4157 HCl salt Usage And Synthesis

Uses	Troriluzole hydrochloride is a third-generation peptide precursor of Riluzole (HY-B0211) and is an orally active glutamate modulator. Troriluzole hydrochloride can reduce synaptic glutamate levels and enhance the uptake of synaptic glutamate. Troriluzole hydrochloride shows potential for treating Alzheimer's disease and Generalized Anxiety Disorder (GAD) [1][2].
References	[1] Schanzer B, et al. Novel investigational therapeutics for generalized anxiety disorder (GAD). Expert Opin Investig Drugs. 2019 Nov;28(11):1003-1012. DOI:10.1080/13543784.2019.1680638 [2] Huang LK, et al. Clinical trials of new drugs for Alzheimer disease. J Biomed Sci. 2020 Jan 6;27(1):18. DOI:10.1186/s12929-019-0609-7

BHV-4157 HCl salt Preparation Products And Raw materials

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