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| | 2,3-Dichloro-6-methoxyquinoxaline Basic information |
| | 2,3-Dichloro-6-methoxyquinoxaline Chemical Properties |
| density | 1.450 | | storage temp. | Inert atmosphere,Room Temperature | | Appearance | White to pink Solid | | InChI | InChI=1S/C9H6Cl2N2O/c1-14-5-2-3-6-7(4-5)13-9(11)8(10)12-6/h2-4H,1H3 | | InChIKey | NFJQDGNCJJPQNV-UHFFFAOYSA-N | | SMILES | N1C2C(=CC(OC)=CC=2)N=C(Cl)C=1Cl |
| | 2,3-Dichloro-6-methoxyquinoxaline Usage And Synthesis |
| Uses | 2,3-Dichloro-6-methoxyquinoxaline is used for preparation of antibacterial and antifungal activity of (tetrazolo[1,5-a]quinoxalinyl)dihydrophthalazine-diones as reactant or reagent. | | Synthesis | General procedure for the synthesis of 2,3-dichloro-6-methoxyquinoxaline from 6-methoxyquinoxaline-2,3-diol: 6-methoxy-1,4-dihydro-quinoxaline-2,3-dione (15.5 g, 1 mmol) was dissolved in 75 mL of phosphorochloride, and the reaction mixture was heated and refluxed for 24 hours. Upon completion of the reaction, a 1:1 mixture of water and methanol was slowly added at 0 to 5 °C to quench the reaction. Subsequently, the resulting precipitate was collected by filtration and dried under reduced pressure to give 17.2 g of 2,3-dichloro-6-methoxyquinoxaline in 93.1% yield. | | References | [1] Patent: KR2018/106597, 2018, A. Location in patent: Paragraph 0451-0454
[2] Journal of Medicinal Chemistry, 2011, vol. 54, # 13, p. 4508 - 4522
[3] Journal of Medicinal Chemistry, 1990, vol. 33, # 8, p. 2240 - 2254 |
| | 2,3-Dichloro-6-methoxyquinoxaline Preparation Products And Raw materials |
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