| Company Name: |
Shanghai Chaolan Chemical Technology Center
|
| Tel: |
021-QQ：65489617 15618227136 |
| Email: |
Sales@ATKchemical.com |
| Products Intro: |
Product Name:MMV666810
CAS:1450666-97-3
Purity:98 Package:1G,5G,10G,50G,100G,500G
|
| Company Name: |
Shanghai Dongyang Biotechnology Co., Ltd.
|
| Tel: |
0512-0512-13601744364 13601744364 |
| Email: |
chemsharker@126.com |
| Products Intro: |
Product Name:MMV666810
CAS:1450666-97-3
Purity:98% Package:1g 5g 10g 25g 50g 100g
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
4008200310 |
| Email: |
marketing@tsbiochem.com |
| Products Intro: |
Product Name:MMV666810
CAS:1450666-97-3
Purity:99.96% Package:5mg/RMB 4920;25mg/RMB 10600;50mg/RMB 13800
|
| Company Name: |
https://hanhongsci.com/
|
| Tel: |
021-54306202 18917919676 |
| Email: |
info@hanhongsci.com |
| Products Intro: |
Product Name:MMV666810
CAS:1450666-97-3
Purity:>=98% Package:5mg;25mg;100mg;1g;5g
|
Methanone, [4-[5-amino-6-[4-(trifluoromethyl)phenyl]-2-pyrazinyl]phenyl](4-hydroxy-1-piperidinyl)- manufacturers
- MMV666810
-
- $2500.00 / 100mg
-
2026-03-24
- CAS:1450666-97-3
- Min. Order:
- Purity: 99.96%
- Supply Ability: 10g
|
| | Methanone, [4-[5-amino-6-[4-(trifluoromethyl)phenyl]-2-pyrazinyl]phenyl](4-hydroxy-1-piperidinyl)- Basic information |
| | Methanone, [4-[5-amino-6-[4-(trifluoromethyl)phenyl]-2-pyrazinyl]phenyl](4-hydroxy-1-piperidinyl)- Chemical Properties |
| Boiling point | 593.5±50.0 °C(Predicted) | | density | 1.364±0.06 g/cm3(Predicted) | | pka | 14.49±0.20(Predicted) |
| | Methanone, [4-[5-amino-6-[4-(trifluoromethyl)phenyl]-2-pyrazinyl]phenyl](4-hydroxy-1-piperidinyl)- Usage And Synthesis |
| Description | MMV666810 is a novel inhibitor of Plasmodium falciparum gametocytes. | | Uses | MMV666810, a 2-aminopyrazine similar to MMV390048, is potent against asexual parasites at 5.94 nM, but against gametocytes, it has a 3.3-fold selectivity to late-stage gametocytes compared to earlier stages (early-stage gametocyte: IC50 603 ± 88 nM; late-stage gametocyte: IC50 179 ± 8 nM). | | References | [1] Niemand J, et al. Chemogenomic Fingerprints Associated with Stage-Specific Gametocytocidal Compound Action against Human Malaria Parasites. ACS Infect Dis. 2021 Oct 8;7(10):2904-2916. DOI:10.1021/acsinfecdis.1c00373 |
| | Methanone, [4-[5-amino-6-[4-(trifluoromethyl)phenyl]-2-pyrazinyl]phenyl](4-hydroxy-1-piperidinyl)- Preparation Products And Raw materials |
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