Propanamide, N-[2-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]ethyl]-N-(4-methoxyphenyl)-

Propanamide, N-[2-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]ethyl]-N-(4-methoxyphenyl)- manufacturers

Propanamide, N-[2-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]ethyl]-N-(4-methoxyphenyl)- Basic information

Product Name:	Propanamide, N-[2-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]ethyl]-N-(4-methoxyphenyl)-
Synonyms:	Propanamide, N-[2-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]ethyl]-N-(4-methoxyphenyl)-;σ1 Receptor/μ Opioid receptor modulator 1
CAS:	2412700-00-4
MF:	C24H31FN2O2
MW:	398.51
EINECS:
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Mol File:	2412700-00-4.mol

Propanamide, N-[2-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]ethyl]-N-(4-methoxyphenyl)- Chemical Properties

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Propanamide, N-[2-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]ethyl]-N-(4-methoxyphenyl)- Usage And Synthesis

Uses	σ1 Receptor/μ Opioid receptor modulator 1 (Compound 44) is a potent σ1 receptor antagonist and μ opioid receptor agonist with Kis of 1.86 nM and 2.1 nM, respectively.σ1 Receptor/μ Opioid receptor modulator 1 exhibits potent analgesic activity. σ1 Receptor/μ Opioid receptor modulator 1 can be used for the research of neuropathic pain[1].
References	[1] Jiaying Xiong, et al. Piperidine propionamide as a scaffold for potent sigma-1 receptor antagonists and mu opioid receptor agonists for treating neuropathic pain. Eur J Med Chem. 2020 Apr 1;191:112144. DOI:10.1016/j.ejmech.2020.112144

Propanamide, N-[2-[4-[(4-fluorophenyl)methyl]-1-piperidinyl]ethyl]-N-(4-methoxyphenyl)- Preparation Products And Raw materials

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