3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-tri(methyl-d3)-10-oxo-7-[(1-oxohexadecyl)oxy]-, inner salt, 4-oxide, (7R)-

Request For Quotation
3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-tri(methyl-d3)-10-oxo-7-[(1-oxohexadecyl)oxy]-, inner salt, 4-oxide, (7R)- Suppliers list
Company Name: Artis Biotech Co. Ltd.  
Tel: 18108108965 18108108965
Email: sales@artisbio.com
Company Name: Shanghai YuanYe Biotechnology Co., Ltd.  
Tel: 15026964105
Email: 2881489226@qq.com
Company Name: CHINA ISOTOPE CO., LIMITED  
Tel: 02151600108 13062666369
Email: info@isotopechem.com
Company Name: Shanghai Saikerui Biotechnology Co. , Ltd.  
Tel: 021-58000709 13120558703
Email: sales@scrbio.com
3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-tri(methyl-d3)-10-oxo-7-[(1-oxohexadecyl)oxy]-, inner salt, 4-oxide, (7R)- Basic information
Product Name:3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-tri(methyl-d3)-10-oxo-7-[(1-oxohexadecyl)oxy]-, inner salt, 4-oxide, (7R)-
Synonyms:3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-tri(methyl-d3)-10-oxo-7-[(1-oxohexadecyl)oxy]-, inner salt, 4-oxide, (7R)-;16:0 PC-d9;[D9]-1,2-Dipalmitoyl-sn-glycero-3-phosphocholine
CAS:77165-56-1
MF:C40H80NO8P
MW:734.05
EINECS:
Product Categories:
Mol File:77165-56-1.mol
3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-tri(methyl-d3)-10-oxo-7-[(1-oxohexadecyl)oxy]-, inner salt, 4-oxide, (7R)- Structure
3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-tri(methyl-d3)-10-oxo-7-[(1-oxohexadecyl)oxy]-, inner salt, 4-oxide, (7R)- Chemical Properties
storage temp. -20°C
solubility Acetonitrile:
Methanol: (1:1): Slightly Soluble: 0.1-1 mg/ml
Methanol: Sparingly Soluble: 1-10 mg/ml
form powder
color White to off-white
InChIKeyKILNVBDSWZSGLL-IFKPPQQBSA-N
SMILES[H][C@@](COP([O-])(OCC[N+](C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=O)(OC(CCCCCCCCCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O
Safety Information
WGK Germany WGK 3
Storage Class11 - Combustible Solids
MSDS Information
3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-tri(methyl-d3)-10-oxo-7-[(1-oxohexadecyl)oxy]-, inner salt, 4-oxide, (7R)- Usage And Synthesis
UsesDPPC-d9-1 is the deuterium labeled DPPC. DPPC (129Y83) is a zwitterionic phosphoglyceride that can be used for the preparation of liposomal monolayers[1]. DPPC-liposome serves effectively as a delivery vehicle for inducing immune responses against GSL antigen in mice[2].
References[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Miller AD. Delivery of RNAi therapeutics: work in progress. Expert Rev Med Devices. 2013 Nov;10(6):781-811. DOI:10.1586/17434440.2013.855471
[3] Akiko Uemura, et al. Induction of immune responses against glycosphingolipid antigens: comparison of antibody responses in mice immunized with antigen associated with liposomes prepared from various phospholipids. J Vet Med Sci. 2005 Dec;67(12):1197-201. DOI:10.1292/jvms.67.1197
[4] CANAY EGE  Ka Y C L. Insertion of Alzheimer’s A beta 40 peptide into lipid monolayers.[J]. Biophysical journal, 2004, 87 3: 1732-1740. DOI: 10.1529/biophysj.104.043265
[5] SUKIT LEEKUMJORN  Amadeu K S. Molecular simulation study of structural and dynamic properties of mixed DPPC/DPPE bilayers.[J]. Biophysical journal, 2006, 90 11: 3951-3965. DOI: 10.1529/biophysj.105.076596
[6] V K KALRA  G S S  S C Sikka. Transport of amino acids in gamma-glutamyl transpeptidase-implanted human erythrocytes.[J]. The Journal of Biological Chemistry, 1981, 256 11: 5567-5571.
3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-tri(methyl-d3)-10-oxo-7-[(1-oxohexadecyl)oxy]-, inner salt, 4-oxide, (7R)- Preparation Products And Raw materials
Tag:3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-tri(methyl-d3)-10-oxo-7-[(1-oxohexadecyl)oxy]-, inner salt, 4-oxide, (7R)-(77165-56-1) Related Product Information
1-Palmitoyl-d9-2-hydroxy-sn-glycero-3-PC 1,2-Dipalmitoyl-13C-sn-glycero-3-PC 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine 1,2-dipalMitoyl-d62-sn-glycero-3-phosphocholine Calcitriol Rapamycin