Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI)

Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI) Suppliers list

Company Name:	BeiJing Hwrk Chemicals Limted
Tel:	0757-86329057 18934348241
Email:	sales4.gd@hwrkchemical.com

Company Name:	Wuhan Chemwish Technology Co., Ltd
Tel:	86-027-67849912
Email:	sales@chemwish.com

Company Name:	Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
Tel:	+86-21-54098501
Email:	sales@sinch.com.cn

Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI) manufacturers

Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI) Basic information

Product Name:	Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI)
Synonyms:	Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI);(R)-3-N-Boc-aminomethylpyrrolidine;tert-Butyl (3R)-pyrrolidin-3-ylmethylcarbamate;R-3-N-Boc-aMinoMethypyrrolidine;tert-butyl N-[(3R)-pyrrolidin-3-ylmethyl]carbamate;(R)-1-pyrrolidin-3-ylmethylcarbamic acid tert-butyl ester;Carbamic acid, N-[(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester;cc-000004
CAS:	173340-25-5
MF:	C10H20N2O2
MW:	200.28
EINECS:
Product Categories:	N-BOC
Mol File:	173340-25-5.mol

Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI) Chemical Properties

Boiling point	303.9±15.0 °C(Predicted)
density	0.997±0.06 g/cm3(Predicted)
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	12.71±0.46(Predicted)
Appearance	white solid

Safety Information

MSDS Information

Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI) Usage And Synthesis

Uses	(R)-tert-butyl pyrrolidin-3-ylmethylcarbamate is a useful reagent in the research discovery of ethyl 5,6-dihydropyrazolo[1,5-c]quinazoline-1-carboxylate, a catalytic inhibitor of DNA gyrase and a potential antibacterial agent.
Synthesis	303111-41-3 173340-25-5 General procedure: tert-butyl (R)-(1-benzylpyrrolidin-3-ylmethyl)carbamate (1.00 g, 3.44 mmol) was mixed with 20% Pd/C and subjected to hydrogenation under hydrogen pressure of 50 psi.After 48 h, the reaction mixture was filtered to remove the catalyst, and the filtrate was concentrated to give 511 mg of tert-butyl (3R)-pyrrolidin-3-methylcarbamate ( Yield: 74%). Mass spectrometry analysis (APCI+): m/z 201 ([M + H]+).
References	[1] Patent: WO2005/49602, 2005, A1. Location in patent: Page/Page column 87; 88; 121 [2] Patent: WO2005/49605, 2005, A1. Location in patent: Page/Page column 115; 116; 149

Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI) Preparation Products And Raw materials

Raw materials

Tag:Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI)(173340-25-5) Related Product Information

6-(tert-Butyl-diMethyl-si... S-1-Cbz-3-(Boc-aminomethyl)-pyrrolidine tert-Butyl (3aS,6aS)-hexahydropyrrolo[3,4-b]pyrrole-5(1H)-carboxylate (S)-1-Benzyl-3-N-Boc-aminomethylpyrrolidine (4-Hydroxymethyl-pyrrolidin-3-ylmethyl)-carbamic acid tert-butyl ester Boc-L-transpro(4-CH2NH-Boc) (S)-N-alpha-(9-Fluorenylmethyloxycarbonyl)-trans-4-(t-butyloxycarbonyl-aminomethyl)-proline cis-5-Benzyl-2-Boc-hexahydropyrrolo[3,4-c]pyrrole tert-Butyl carbamate Tert-butyl 2,6-diazaspiro[3.4]octane-2-carboxylate cis-2-Boc-hexahydropyrrolo[3,4-c]pyrrole Carbamic acid, [(3R)-3-pyrrolidinylmethyl]-, 1,1-dimethylethyl ester (9CI)