6-Chloro-3-nitroquinolin-4-ol manufacturers
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| | 6-Chloro-3-nitroquinolin-4-ol Basic information |
| Product Name: | 6-Chloro-3-nitroquinolin-4-ol | | Synonyms: | 6-CHLORO-3-NITROQUINOLIN-4-OL;4-Quinolinol,6-chloro-3-nitro-;6-chloro-3-nitro-4-Quinolinol;6-chloro-3-nitro-1H-quinolin-4-one;6-Chloro-3-nitroquinolin-4-ol, CAS 101861-61-4 | | CAS: | 101861-61-4 | | MF: | C9H5ClN2O3 | | MW: | 224.6 | | EINECS: | | | Product Categories: | | | Mol File: | 101861-61-4.mol |  |
| | 6-Chloro-3-nitroquinolin-4-ol Chemical Properties |
| storage temp. | Sealed in dry,Room Temperature | | Appearance | White to off-white Solid |
| | 6-Chloro-3-nitroquinolin-4-ol Usage And Synthesis |
| Synthesis | Step 2: Synthesis of 6-chloro-3-nitroquinolin-4-ol
To a 500 mL round bottom flask was added 5-chloro-2-(2-nitroethylideneamino)benzoic acid (25 g, 0.10 mol), K2CO3 (42.6 g, 0.30 mol) and acetic anhydride (250 mL). The reaction mixture was heated to 90 °C and the reaction was stirred at this temperature for 1 hour. Upon completion of the reaction, the resulting solid product was collected by filtration, washed sufficiently with deionized water to remove residual reactants and salts, and subsequently dried to afford 17.5 g (76% yield) of 6-chloro-3-nitroquinolin-4-ol as a gray solid. The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 9.12 (s, 1H), 8.15 (s, 1H), 7.72 (s, 2H). Mass spectral analysis showed m/z: 224 (M+H+). | | References | [1] Patent: US2010/120741, 2010, A1. Location in patent: Page/Page column 93
[2] Patent: WO2011/112731, 2011, A2. Location in patent: Page/Page column 199-200 |
| | 6-Chloro-3-nitroquinolin-4-ol Preparation Products And Raw materials |
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