FOY 251 manufacturers
- FOY 251
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- $30.00
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2026-07-27
- CAS:71079-09-9
- Purity: 97.11%
- Supply Ability: 10g
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| | FOY 251 Basic information |
| Product Name: | FOY 251 | | Synonyms: | FOY 251;4-(4-guanidinobenzoyloxy)phenylacetic acid;4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]-benzeneacetic Acid Monomethanesulfonate;4-[[4-[(Aminoiminomethyl)amino]benzoyl]oxy]-benzeneacetic Acid Monomethanesulfonat;FOY 251（Camostat metabolite）;FOY-251 mesylate;2-(4-((4-Guanidinobenzoyl)oxy)phenyl)acetic acid methanesulfonic acid salt;Benzeneacetic acid,4-[[4-[(aminoiminomethyl)- amino]benzoyl]oxy]-,monomethanesulfonate | | CAS: | 71079-09-9 | | MF: | C17H19N3O7S | | MW: | 409.41 | | EINECS: | | | Product Categories: | Amine;Aromatics;Inhibitors;Metabolites & Impurities;Chemical Amines | | Mol File: | 71079-09-9.mol |  |
| | FOY 251 Chemical Properties |
| Melting point | 194-198°C | | storage temp. | Inert atmosphere,2-8°C | | solubility | DMSO (Slightly), Methanol (Slightly) | | form | Solid | | color | White to Off-White | | Water Solubility | Water: < 0.1 mg/mL (insoluble) | | InChIKey | JXMOPIDYHUYOED-UHFFFAOYSA-N | | SMILES | O=C(C1=CC=C(NC(N)=N)C=C1)OC2=CC=C(CC(O)=O)C=C2.O=S(O)(C)=O |
| WGK Germany | WGK 3 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral
Skin Irrit. 2 |
| | FOY 251 Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | A metabolite of Camostat. It is a pollen protease inhibitor for prevention and control of allergy. | | Biological Activity | Trypsin-like serine protease inhibitor Camost at (FOY-305) active metabolite with inhibitory potency against transmembrane serine protease 2 (TMPRSS2).
FOY-251 is a trypsin-like serine protease inhibitor and an active metabolite of the oral drug Camostat/FOY-305 (trypsin IC50 = 51/55 nM by FOY-305/FOY-251; plasma kallikrein/plasmin IC50 = 1.48/2.64 μM by FOY-305 and 2.32/12.5 μM by FOY-251). FOY-251 and FOY-305 are also potent inhibitor against transmembrane serine protease 2 (TMPRSS2 IC50 = 6.2/33.3 nM by by FOY-305/FOY-251) th at primes SARS-CoV-2 spike protein for host cell entry. |
| | FOY 251 Preparation Products And Raw materials |
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