伊培沙宗
| 中文名称 | 伊培沙宗 |
|---|---|
| 中文同义词 | 伊培沙宗;化合物 T15591 |
| 英文名称 | Ipenoxazone |
| 英文同义词 | (4S,5R)-3-[3-(Hexahydro-1H-azepin-1-yl)propyl]-4-(2-methylpropyl)-5-phenyl-2-oxazolidinone;Ipenoglan;NC-1200;Ipenoxazone;MLV 6976;2-Oxazolidinone, 3-[3-(hexahydro-1H-azepin-1-yl)propyl]-4-(2-methylpropyl)-5-phenyl-, (4S,5R)- |
| CAS号 | 104454-71-9 |
| 分子式 | C22H34N2O2 |
| 分子量 | 358.52 |
| EINECS号 | |
| 相关类别 | |
| Mol文件 | 104454-71-9.mol |
| 结构式 |  |
伊培沙宗 性质
| 储存条件 | Store at -20°C |
|---|---|
| 溶解度 | 溶于二甲基亚砜 |
Ipenoxazone 是一种强效的中枢性肌肉松弛剂。
Ipenoxazone is a potent and centrally acting muscle relaxant. An intravenous injection of 2 mg/kg Ipenoxazone causes a reduction of electromyographic activity which reaches a maximum within 3 min after the injection. Within 1 min after the injection of Ipenoxazone at a dose of 4 mg/kg, the blood pressure changes from a control level of 138±9 mmHg to a minimum level of 98±9 mmHg (n=6) but it rapidly returns to the control level within 1 to 2 min, while the rigidity is still reduced significantly at that time. High doses (greater than 30 mg/kg i.p.) of Ipenoxazone produces a transient and dose-dependent sedation in almost all mice about 5 min after its administration.