- 7-Chloroindole
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- $36.00
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2026-09-02
- CAS:53924-05-3
- Min. Order: 1kg
- Purity: 99%
- 7-Chloroindole
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- $1.10
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2026-08-20
- CAS:53924-05-3
- Min. Order: 1g
- Purity: 99.0% Min
- Supply Ability: 100 Tons
- 7-Chloroindole
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-
2026-01-29
- CAS:53924-05-3
- Min. Order: 1g
- Purity: 98%
- Supply Ability: 500kg
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| | 7-Chloroindole Basic information |
| | 7-Chloroindole Chemical Properties |
| Melting point | 55-58 °C(lit.) | | Boiling point | 90-95 °C0.25 mm Hg(lit.) | | density | 1.1976 (rough estimate) | | refractive index | 1.5660 (estimate) | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | soluble in Methanol | | pka | 15.42±0.30(Predicted) | | form | powder to crystal | | color | White to Light yellow to Dark green | | BRN | 114743 | | InChI | InChI=1S/C8H6ClN/c9-7-3-1-2-6-4-5-10-8(6)7/h1-5,10H | | InChIKey | WMYQAKANKREQLM-UHFFFAOYSA-N | | SMILES | N1C2=C(C=CC=C2Cl)C=C1 | | CAS DataBase Reference | 53924-05-3(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36 | | WGK Germany | 3 | | HazardClass | IRRITANT | | HS Code | 29339990 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 7-Chloroindole Usage And Synthesis |
| Chemical Properties | Beige-yellowish powder | | Uses | 7-Chloroindole may be used in the preparation of 1-methyl-7-chloroindole and glycosylated 7-chloroindole-3-acetamide. | | General Description | 7-Chloroindole is an indole derivative. It has been synthesized from 2,3-dihydroindole. | | Synthesis | 3-Chloro-2-nitrotoluene (2 mmol) was dissolved in 20 mL of acetonitrile and DMFDMA (480 mg, 4 ) was added.
DMFDMA (480 mg, 4 ) was added and refluxed at elevated temperature for 5 h. The reaction was monitored by TLC, cooled, concentrated under reduced pressure, and the residue was washed with water and a small amount of ethanol to give Intermediate 4. Intermediate 4 was added to 50 mL of 10% hydrazine in methanol.
Intermediate 4 was added into 50mL of 10% hydrazine in methanol solution, warmed to 50, and reacted for 8h, and the reaction was monitored by TLC .
The reaction was completed, cooled to room temperature, concentrated under reduced pressure and purified by column chromatography (petroleum ether:ethyl acetate 20:1) to obtain the target compound. The product data were as follows: white solid, yield 57%. |
| | 7-Chloroindole Preparation Products And Raw materials |
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