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| | 1H-Pyrazole-4-carboxamide,3-amino-1-methyl-(9CI) Basic information |
| Product Name: | 1H-Pyrazole-4-carboxamide,3-amino-1-methyl-(9CI) | | Synonyms: | 1H-Pyrazole-4-carboxamide,3-amino-1-methyl-(9CI);3-Amino-1-methyl-1H-pyrazole-4-carboxylic acid amide;1H-Pyrazole-4-carboxamide, 3-amino-1-methyl-;3-Amino-1-methylpyrazole-4-carboxamide;3-amino-1-methyl-1H-Pyrazole-4-carboxamide | | CAS: | 89181-79-3 | | MF: | C5H8N4O | | MW: | 140.14 | | EINECS: | | | Product Categories: | AMIDE | | Mol File: | 89181-79-3.mol |  |
| | 1H-Pyrazole-4-carboxamide,3-amino-1-methyl-(9CI) Chemical Properties |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| | 1H-Pyrazole-4-carboxamide,3-amino-1-methyl-(9CI) Usage And Synthesis |
| Synthesis | GENERAL PROCEDURE: 1-methyl-3-amino-4-cyanopyrazole (0.03 mol) was dissolved in 7 mL of concentrated hydrochloric acid at 0°C and stirred at room temperature for 5 hours. After completion of the reaction, the mixture was poured into ice water and neutralized with 28% ammonia solution to pH 7. The precipitated white precipitate was washed with cold water and dried under vacuum. | | References | [1] Bioorganic and Medicinal Chemistry, 2014, vol. 22, # 5, p. 1751 - 1765
[2] European Journal of Medicinal Chemistry, 2015, vol. 92, p. 784 - 798
[3] Patent: WO2012/30924, 2012, A1. Location in patent: Page/Page column 134 |
| | 1H-Pyrazole-4-carboxamide,3-amino-1-methyl-(9CI) Preparation Products And Raw materials |
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