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| | 5-BROMO-2-IODO-M-XYLENE Basic information |
| Product Name: | 5-BROMO-2-IODO-M-XYLENE | | Synonyms: | 5-BROMO-2-IODO-1,3-XYLENE;5-BROMO-2-IODO-3-XYLENE;5-BROMO-2-IODO-M-XYLENE;2,6-diMethyl-4-broMo-iodobenzene;5-Bromo-1,3-dimethyl-2-iodobenzene 98+%;Benzene,5-broMo-2-iodo-1,3-diMethyl-;5-Bromo-1,3-dimethyl-2-iodobenzene;1-Bromo-3,5-dimethy-4-iodobezene | | CAS: | 206559-43-5 | | MF: | C8H8BrI | | MW: | 310.96 | | EINECS: | 606-594-3 | | Product Categories: | | | Mol File: | 206559-43-5.mol |  |
| | 5-BROMO-2-IODO-M-XYLENE Chemical Properties |
| Melting point | 42 °C | | Boiling point | 282℃ | | density | 1.940 | | Fp | 125℃ | | storage temp. | Keep in dark place,Sealed in dry,2-8°C | | form | fused solid | | color | Faint peach | | CAS DataBase Reference | 206559-43-5(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-36/37/39 | | HazardClass | IRRITANT | | HS Code | 2903998090 |
| | 5-BROMO-2-IODO-M-XYLENE Usage And Synthesis |
| Synthesis | The diazotization reaction was carried out using sodium nitrite and hydrochloric acid in acetonitrile solvent at 0 °C using 4-bromo-2,6-dimethylaniline as starting material. Subsequently, the diazonium group was converted to iodine by addition of potassium iodide to afford the target product 5-bromo-2-iodo-1,3-xylene in 96% yield. The synthesis was described with reference to known literature (NonPatentDocument 2). | | References | [1] Journal of Medicinal Chemistry, 2018, vol. 61, # 16, p. 7202 - 7217
[2] Patent: JP5959171, 2016, B2. Location in patent: Paragraph 0258-0260
[3] Bulletin of the Chemical Society of Japan, 2001, vol. 74, # 11, p. 2207 - 2218
[4] Patent: WO2009/74314, 2009, A1. Location in patent: Page/Page column 168-169 |
| | 5-BROMO-2-IODO-M-XYLENE Preparation Products And Raw materials |
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