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| Product Name: | AK 295 | | Synonyms: | Carbamic acid, N-[(1S)-1-[[[1-ethyl-3-[[3-(4-morpholinyl)propyl]amino]-2,3-dioxopropyl]amino]carbonyl]-3-methylbutyl]-, phenylmethyl ester;CX 295;CX295;CX-295 | | CAS: | 160399-35-9 | | MF: | C26H40N4O6 | | MW: | 504.62 | | EINECS: | | | Product Categories: | | | Mol File: | 160399-35-9.mol |  |
| | AK 295 Chemical Properties |
| form | Solid | | color | White to off-white |
| | AK 295 Usage And Synthesis |
| Description | AK 295, also known asCX 295, is a dipeptide alpha-ketoamide calpain inhibitor. | | Uses | AK 295 (CX 295) is a calpain inhibitor that inhibits apoptosis through a calpain-dependent pathway. AK 295 improves neurological function in a rat model of spinal cord injury (SCI). AK 295 can be used in the study of neurodegenerative diseases, such as bulbar amyotrophy, stroke, Alzheimer's disease, Parkinson's disease, multiple sclerosis[1]. | | References | [1] Colak A, et al. Calpain inhibitor AK 295 inhibits calpain-induced apoptosis and improves neurologic function after traumatic spinal cord injury in rats. Neurocirugia (Astur). 2009 Jun;20(3):245-54. PMID:19575128 |
| | AK 295 Preparation Products And Raw materials |
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